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reblastatin

structure in first source

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Quinones: 434
  - reblastatin: 3

Experts

1.	Eichner, Simone: 1 article (01/2019)
2.	Hermane, Jekaterina: 1 article (01/2019)
3.	Kirschning, Andreas: 1 article (01/2019)
4.	Mancuso, Lena: 1 article (01/2019)
5.	Sasse, Florenz: 1 article (01/2019)
6.	Schröder, Benjamin: 1 article (01/2019)
7.	Zeilinger, Carsten: 1 article (01/2019)
8.	Dong, Yilong: 1 article (06/2017)
9.	Jiang, Mingxing: 1 article (06/2017)
10.	Lu, Tao: 1 article (06/2017)

Related Diseases

1.

Neoplasms (Cancer)

01/01/2019 - "Among these, the first thiophene derivative of reblastatin showed strong antiproliferative activity towards several human cancer cell lines. "
05/07/2010 - "Both reblastatin (1) and autolytimycin (2) were shown to bind the heat shock protein 90 with enhanced binding activity (approximately 25 nM) than 17-allylamino-17-demethoxygeldanamycin (17-AAG, 4), a geldanamycin (3) derivative currently under evaluation for treatment of cancer (approximately 100 nM)."
06/20/2017 - "Streptomyces autolyticus CGMCC 0516 produces the anti-tumor benzoquinone ansamycins geldanamycin, autolytimycin, and reblastatin and the 16-membered macrodiolide elaiophylin. "

Related Drugs and Biologics

1.	autolytimycin
2.	geldanamycin
3.	Macrocyclic Lactams
4.	Thiophenes
5.	Heat-Shock Proteins (Heat-Shock Protein)
6.	tanespimycin (17AAG)
7.	elaiophylin
8.	quinone (benzoquinone)