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phenylalanyl-glycyl-NHO-Bz

induces apoptosis in human cancer cells

Also Known As:

CATI-1; Z-Phe-Gly-NHO-Bz; cathepsin inhibitor I

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - Dipeptides: 945
      - phenylalanyl-glycyl-NHO-Bz: 1

Experts

1.	Uckun, F M: 1 article (05/2000)
2.	Zhu, D M: 1 article (05/2000)

Related Diseases

1.

Neoplasms (Cancer)

05/01/2000 - "The exquisite sensitivity of human cancer cells to CATI-1 indicates that this compound and its derivatives may provide the basis for new treatment programs against a broad spectrum of malignancies."
05/01/2000 - "Here we provide experimental evidence that the cathepsin inhibitor Z-Phe-Gly-NHO-Bz induces rapid apoptotic death in human cancer cell lines. "
05/01/2000 - "Z-Phe-Gly-NHO-Bz, an inhibitor of cysteine cathepsins, induces apoptosis in human cancer cells."

Related Drugs and Biologics

1.	Cysteine (L-Cysteine)
2.	Cathepsins