monophenolase

polyphenol oxidase from iceberg lettuce shows monophenolase activity, predominantly located in the chloroplast thylakoid membranes

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

1.	Melanoma (Melanoma, Malignant) 08/15/2022 - "Tyrosinase (TYR) monophenolase activity plays a key role in the development of diseases such as melanoma. " 12/01/2000 - "Investigation to purify a similar type of protein from B16 murine melanoma tumours by following the same purification procedure resulted in a partially purified protein with a molecular weight of 66 kDa. However, unlike MP 66, this protein did not show inhibition of the monophenolase activity of tyrosinase at pH 6.8. " 02/01/2015 - "In the present study, we conducted a comprehensive kinetic analysis to understand the mechanisms of inhibition imposed by 2-amino benzoic acid, 4-amino benzoic acid, nicotinic acid, and picolinic acid on the monophenolase and diphenolase activities of the mushroom tyrosinase, and then MTT assay was exploited to evaluate their toxicity on the melanoma cells. "
2.	Breast Neoplasms (Breast Cancer) 01/01/2018 - "The inhibitory effects of four series of aryl butene derivatives, active against breast cancer, on the monophenolase activity of tyrosinase, in melanin-free ink from Sepia officinalis, have been studied. "

1.	Monophenol Monooxygenase (Tyrosinase)
2.	Benzoic Acid (Potassium Benzoate)
3.	Niacin (Nicotinic Acid)
4.	picolinic acid (chromium picolinate)
5.	Proteins (Proteins, Gene)
6.	Melanins (Melanin)
7.	butylene