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peptide F4.2

peptide fragment of HLA-A31

Also Known As:

F4.2 peptide; YSWMDISCWI; antigenic peptide F4.2

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Glycoproteins: 24834
    - Membrane Glycoproteins: 2252
      - Histocompatibility Antigens Class I: 1944
        HLA-A Antigens: 2452
        peptide F4.2: 3
  - Membrane Proteins: 10078
    - Membrane Glycoproteins: 2252
      - Histocompatibility Antigens Class I: 1944
        HLA-A Antigens: 2452
        peptide F4.2: 3
- Peptides: 82426
  - Peptide Fragments: 373
    - peptide F4.2: 3
Carbohydrates: 22023
- Glycoconjugates: 1353
  - Glycoproteins: 24834
    - Membrane Glycoproteins: 2252
      - Histocompatibility Antigens Class I: 1944
        HLA-A Antigens: 2452
        peptide F4.2: 3
Biological Factors: 2472
- Antigens: 143924
  - Surface Antigens: 5813
    - Histocompatibility Antigens: 1132
      - HLA Antigens: 8934
        HLA-A Antigens: 2452
        peptide F4.2: 3
      - Histocompatibility Antigens Class I: 1944
        HLA-A Antigens: 2452
        peptide F4.2: 3
  - Isoantigens: 1221
    - Histocompatibility Antigens: 1132
      - HLA Antigens: 8934
        HLA-A Antigens: 2452
        peptide F4.2: 3
      - Histocompatibility Antigens Class I: 1944
        HLA-A Antigens: 2452
        peptide F4.2: 3

Experts

1.	Hirohashi, Y: 2 articles (06/2000 - 01/2000)
2.	Kondo, H: 2 articles (06/2000 - 01/2000)
3.	Nabeta, Y: 2 articles (06/2000 - 01/2000)
4.	Sahara, H: 2 articles (06/2000 - 01/2000)
5.	Sato, N: 2 articles (06/2000 - 01/2000)
6.	Sato, Y: 2 articles (06/2000 - 01/2000)
7.	Hirohashi, Yoshihiko: 1 article (05/2002)
8.	Ichimiya, Shingo: 1 article (05/2002)
9.	Jimbow, Kouichi: 1 article (05/2002)
10.	Kikuchi, Kokichi: 1 article (05/2002)

Related Diseases

1.	Stomach Neoplasms (Stomach Cancer) 06/01/2000 - "These results suggest that F4.2 peptide may be useful as an HLA-A31-restricted peptide vaccine in certain patients with gastric cancer." 01/01/2000 - "Some stomach cancer lines into which the HLA-A31 gene had been introduced, such as MKN28-A31-2, were lysed by TcHST-2, suggesting the presence of F4.2 peptide in at least some HLA-A31(+) stomach cancers. " 01/01/2000 - "Furthermore, F4.2 peptide induced an F4.2 peptide-specific CTL response in at least 30-40% of HLA-A31(+) peripheral blood lymphocytes from gastric cancer patients, suggesting that F4.2 peptide could be used as a cancer vaccine for gastric tumors. "
2.	Signet Ring Cell Carcinoma 05/01/2002 - "We previously reported acid-extracted natural antigenic peptide (F4.2 [YSWMDISCWI]) of a gastric signet ring cell carcinoma HST-2 cells, recognized by HLA-A*31012-restricted autologous cytotoxic T lymphocytes, TcHST-2 line. "
3.	Neoplasms (Cancer) 01/01/2000 - "Furthermore, F4.2 peptide induced an F4.2 peptide-specific CTL response in at least 30-40% of HLA-A31(+) peripheral blood lymphocytes from gastric cancer patients, suggesting that F4.2 peptide could be used as a cancer vaccine for gastric tumors. "

Related Drugs and Biologics

1.	peptide F4.2
2.	Cancer Vaccines
3.	HLA-A Antigens (HLA-A)
4.	Acids
5.	Protein Subunit Vaccines
6.	HLA-A31 antigen