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demethylclozapine
metabolite of clozapine
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
3-Ring Heterocyclic Compounds
Dibenzazepines: 4
Clozapine: 6662
demethylclozapine: 1
Related Diseases
1.
Body Weight (Weight, Body)
11/01/1999 - "
When comparing their clozapine dose and body weight-related serum drug levels, we found that clozapine and demethylclozapine concentrations were about 40% lower in the smoking than in the non-smoking group, probably due to an inducing effect of smoking on the cytochrome P450 (CYP) 1A2, which is involved in the metabolism of clozapine.
"
Related Drugs and Biologics
1.
Cytochrome P-450 CYP1A2 (CYP1A2)
2.
Cytochrome P-450 Enzyme System (Cytochrome P450)
3.
Clozapine (Clozaril)