|1.||De Naeyer, An: 2 articles (09/2011 - 11/2004)|
|2.||De Keukeleire, Denis: 2 articles (09/2011 - 11/2004)|
|3.||Haegeman, Guy: 2 articles (09/2011 - 11/2004)|
|4.||Na, Kwang-Min: 1 article (04/2013)|
|5.||Oh, Ikhoon: 1 article (04/2013)|
|6.||Kim, Byung-Hak: 1 article (04/2013)|
|7.||Shin, Jongheon: 1 article (04/2013)|
|8.||Lee, Yun Sang: 1 article (04/2013)|
|9.||Kim, Tae-Yoon: 1 article (04/2013)|
|10.||Song, Inn-Hye: 1 article (04/2013)|
|1.||Brain Ischemia (Cerebral Ischemia)
|2.||Chronic Hepatitis B
04/15/2013 - "This study provides new evidence that kurarinone may ameliorate chronic inflammatory skin diseases through the suppression of pathogenic CD4(+) T-cell differentiation and the overall immune response."
04/15/2013 - "In two established animal models of chronic inflammatory skin disease, one in which psoriasis-like skin disease was induced by an interleukin 23 (IL-23) injection into mouse ears and another in which 2,4,6-trinitrochlorobenzene (TNCB) application on the abdomens of mice was used to induce contact dermatitis, kurarinone repressed disease development by inhibiting the expression of pro-inflammatory mediators, including cytokines, chemokines and enzyme in murine ear skin. "
06/01/2007 - "To study the effect of Kurarinone on renal tubular epithelial cell-mesenchyma (ECM) trans-differentiation in rats with renal interstitial fibrosis and to explore its possible mechanisms. "
06/01/2007 - "[Effect of kurarinone on renal tubular epithelial cell-mesenchyma trans-differentiation in rats with renal interstitial fibrosis]."
11/30/2012 - "These data suggest that kurarinone sensitizes TRAIL-induced tumor cell apoptosis via suppression of NF-κB-dependent cFLIP expression, indicating that this compound can be used as an anti-tumor agent in combination with TRAIL."
11/30/2012 - "A low dose of kurarinone had no significant effect on apoptosis, but this compound markedly promoted tumor cell death through elevation of Bid cleavage, cytochrome c release release and caspase activation in HeLa cells treated with TRAIL. "
09/01/2011 - "Attenuation of ERK/RSK2-driven NFκB gene expression and cancer cell proliferation by kurarinone, a lavandulyl flavanone isolated from Sophora flavescens ait. "
09/01/2011 - "We have analyzed in molecular detail how kurarinone, a lavandulyl flavanone isolated from Sophora flavescens, suppresses nuclear factor-κB (NFκB)-driven interleukin-6 (IL6) expression and cancer cell growth. "
09/01/2011 - "Our results in estrogen-unresponsive fibroblasts, ribosomal S6 kinase 2 kinase (RSK2) knockout cells, and estrogen receptor (ER)-deficient breast tumor cells show that kurarinone can inhibit tumor cell proliferation and selectively block nuclear NFκB transactivation of specific target genes such as IL6, cyclin D1, SOD2 but not TNFAIP2. "
|2.||Interferon-alpha (Interferon Alfa)
|4.||Interleukin-23 (Interleukin 23)
|5.||Cytochromes c (Cytochrome c)
|9.||Interleukin-6 (Interleukin 6)