HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

cinnamamide

structure in first source

Also Known As:

2-Propenamide, 3-phenyl-, (2E)-

Networked: 14 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Cinnamates: 48
      - cinnamamide: 14

Experts

1.	Gunia-Krzyżak, Agnieszka: 4 articles (09/2022 - 08/2015)
2.	Marona, Henryk: 3 articles (06/2020 - 08/2015)
3.	Koczurkiewicz-Adamczyk, Paulina: 2 articles (09/2022 - 06/2020)
4.	Pękala, Elżbieta: 2 articles (09/2022 - 06/2020)
5.	Słoczyńska, Karolina: 2 articles (09/2022 - 06/2020)
6.	Nitek, Wojciech: 2 articles (06/2020 - 01/2017)
7.	Żesławska, Ewa: 2 articles (06/2020 - 01/2017)
8.	Tu, Yuanbiao: 2 articles (01/2017 - 04/2016)
9.	Waszkielewicz, Anna M: 2 articles (01/2017 - 08/2015)
10.	Xu, Shan: 2 articles (01/2017 - 04/2016)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2017 - "Structure-activity relationships (SARs) and docking studies indicated that replacement of the cinnamamide group by aryl semicarbazone scaffolds slightly decreased the anti-tumor activity. " 09/15/2022 - "Cinnamamide derivatives with 4-hydroxypiperidine moiety enhance effect of doxorubicin to cancer cells and protect cardiomyocytes against drug-induced toxicity through CBR1 inhibition mechanism." 04/01/2016 - "Two series of afatinib derivatives bearing cinnamamide moiety (10a-n and 11a-h) were designed, synthesized and evaluated for the IC50 values against four cancer cell lines (A549, PC-3, MCF-7 and Hela). " 01/01/1999 - "When administered i.p., cinnamamide not only inhibited the growth of transplanted tumors but also reduced the number of lung metastases in mice bearing Lewis lung carcinoma. "
2.	Muscle Spasticity (Spastic) 01/01/1977 - "[Electromyographic studies on the effect of the cinnamamide derivative LCB-29 in spastic syndromes (author's transl)]."
3.	Epilepsy (Aura) 06/19/2020 - "Cinnamamide derivatives were identified in preclinical as well as clinical studies as important drug candidates for the treatment of epilepsy. " 06/19/2020 - "The cinnamamide derivative presented here: S(+)-(2E)-N-(2-hydroxypropyl)-3-phenylprop-2-enamide (S(+)-N-(2-hydroxypropyl)cinnamamide, compound KM-568) showed anticonvulsant activity in several models of epilepsy and seizures in mice and rats. " 06/19/2020 - "S(+)-(2E)-N-(2-Hydroxypropyl)-3-Phenylprop-2-Enamide (KM-568): A Novel Cinnamamide Derivative with Anticonvulsant Activity in Animal Models of Seizures and Epilepsy."
4.	Acute Lung Injury 03/24/2016 - "Discovery of a New Inhibitor of Myeloid Differentiation 2 from Cinnamamide Derivatives with Anti-Inflammatory Activity in Sepsis and Acute Lung Injury."
5.	Lewis Lung Carcinoma 01/01/1999 - "When administered i.p., cinnamamide not only inhibited the growth of transplanted tumors but also reduced the number of lung metastases in mice bearing Lewis lung carcinoma. "

Related Drugs and Biologics

1.	Semicarbazones
2.	Cholinergic Agents (Cholinergics)
3.	Doxorubicin (Adriamycin)
4.	Antioxidants
5.	Anticonvulsants (Antiepileptic Drugs)
6.	Amides
7.	Afatinib
8.	celastrol
9.	barbituric acid (barbiturate)
10.	pyridine