carboxymethylpullulan

Networked: 5 relevant articles (1 outcomes, 0 trials/studies)

1.	Neoplasms (Cancer) 10/01/1997 - "In vivo antitumor effects of the conjugates of doxorubicin (DXR) with carboxymethylpullulan (CMPul) through tetrapeptide spacers were compared with those of DXR against tumor-bearing rats. " 05/01/2000 - "Distribution characteristics of carboxymethylpullulan-peptide-doxorubicin conjugates in tumor-bearing rats: different sequence of peptide spacers and doxorubicin contents." 12/01/2000 - "The antitumor efficacy of the conjugate of doxorubicin (DXR) and carboxymethylpullulan (CMPul) with Phe-Gly spacer (CMPul-FG-DXR) was evaluated using murine tumor models and compared with that of DXR. "
2.	Edema (Dropsy) 01/01/2000 - "Sialyl Lewis X (SLe(x)), an E-selectin ligand, was conjugated with carboxymethylpullulan (CMPul) and the disposition characteristics of this conjugate after intravenous administration were investigated using mice with ear edema. "
3.	Carcinosarcoma 05/01/2000 - "Plasma and tissue distribution of conjugates of carboxymethylpullulan (CMPul) and doxorubicin (DXR), either bound directly or through three types of tetrapeptide spacers, was studied after intravenous injection to rats bearing Walker 256 carcinosarcoma and compared with that of DXR. "
4.	Autoimmune Diseases (Autoimmune Disease) 02/01/2001 - "To demonstrate the potential of carboxymethylpullulan (CMPul) as a carrier for targeting immune tissues, and to find whether immune tissues could be set as the target of an immunosuppressant to treat autoimmune diseases. "

1.	Doxorubicin (Adriamycin)
2.	carboxymethylpullulan- phenylglycyl- doxorubicin conjugate
3.	phenylalanylglycine
4.	E-Selectin
5.	Peptides (Polypeptides)
6.	Ligands
7.	Immunosuppressive Agents (Immunosuppressants)
8.	Sialyl Lewis X Antigen

1.	Intravenous Administration
2.	Intravenous Injections