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O-desulfated heparin

Also Known As:

heparin, O-desulfated

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Polysaccharides: 15383
  - Glycosaminoglycans: 5640
    - Heparin: 24996
      - O-desulfated heparin: 6

Experts

1.	Kennedy, Thomas P: 2 articles (12/2007 - 11/2005)
2.	Batchinsky, Andriy I: 1 article (01/2022)
3.	Cancio, Leopoldo C: 1 article (01/2022)
4.	Cancio, Tomas S: 1 article (01/2022)
5.	Edsall, Peter R: 1 article (01/2022)
6.	Li, Yansong: 1 article (01/2022)
7.	Liu, Bin: 1 article (01/2022)
8.	Simovic, Milomir O: 1 article (01/2022)
9.	Yang, Zhangsheng: 1 article (01/2022)
10.	Connolly, E Sander: 1 article (12/2007)

Related Diseases

1.	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 12/01/2007 - "In this study, we examined whether or not administration of a novel O-desulfated heparin (ODSH), with significantly decreased anticoagulant activity but active anti-inflammatory effects, would ameliorate inflammatory neurological injury without increasing intracerebral hemorrhage in a rat model of transient middle cerebral artery occlusion. "
2.	Cerebral Hemorrhage 12/01/2007 - "In this study, we examined whether or not administration of a novel O-desulfated heparin (ODSH), with significantly decreased anticoagulant activity but active anti-inflammatory effects, would ameliorate inflammatory neurological injury without increasing intracerebral hemorrhage in a rat model of transient middle cerebral artery occlusion. "
3.	Reperfusion Injury 12/01/2007 - "O-desulfated heparin improves outcome after rat cerebral ischemia/reperfusion injury." 11/15/2005 - "O-Desulfated heparin (ODSH) is a promising new anti-inflammatory agent for the prevention of reperfusion injury following myocardial infarction or stroke. " 07/01/1997 - "Selectively O-desulfated heparin also inhibits complement lysis of erythrocytes, prevents ischemia-reperfusion injury of the lung, remains a potent antiproliferative treatment for cultured airway smooth muscle and normalizes altered neuronal M2 muscarinic receptor sensitivity and bronchial hyperreactivity after antigen challenge. "
4.	Myocardial Infarction 11/15/2005 - "O-Desulfated heparin (ODSH) is a promising new anti-inflammatory agent for the prevention of reperfusion injury following myocardial infarction or stroke. " 06/01/2000 - "When given at the time of coronary artery reperfusion in a canine model of myocardial infarction, heparin or o-desulfated heparin equally reduced neutrophil adherence to ischemic-reperfused coronary artery endothelium, influx of neutrophils into ischemic-reperfused myocardium, myocardial necrosis, and release of creatine kinase into plasma. "
5.	Stroke (Strokes) 11/15/2005 - "O-Desulfated heparin (ODSH) is a promising new anti-inflammatory agent for the prevention of reperfusion injury following myocardial infarction or stroke. "

Related Drugs and Biologics

1.	Anticoagulants
2.	Heparin (Liquaemin)
3.	Muscarinic M2 Receptor
4.	HMGB1 Protein (HMG1)
5.	Creatine Kinase (Creatine Phosphokinase)
6.	Complement System Proteins (Complement)
7.	Antigens
8.	Anti-Inflammatory Agents (Anti-Inflammatories)
9.	N-desulfated heparin