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OFU 001
structure in first source
Also Known As:
1-(2'-oxopropyl)-5-fluorouracil; OFU001
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Pyrimidines: 510
Pyrimidinones: 71
Uracil: 1493
Fluorouracil: 26711
OFU 001: 1
Experts
1.
Hatta, H
: 1 article (02/2001)
2.
Mori, M
: 1 article (02/2001)
3.
Nishimoto, S I
: 1 article (02/2001)
4.
Shibamoto, Y
: 1 article (02/2001)
5.
Zhou, L
: 1 article (02/2001)
Related Diseases
1.
Neoplasms (Cancer)
02/01/2001 - "
Administration of OFU001 (100-200 mg/kg) to the tumor-bearing mice before a single dose of 15-Gy irradiation produced a mean tumor growth delay of 1-5 days as compared to radiation alone (although the delay was not significant).
"
02/01/2001 - "
To evaluate in vivo efficacy, OFU001 was administered 30 min before irradiation, and radiation-potentiating effects were investigated by means of a tumor growth delay assay and a 50% tumor control dose (TCD-50) assay.
"
02/01/2001 - "
Following administration of OFU001 and irradiation at 30 Gy, the average 5-FU levels in the tumor and serum were 179 ng/g and 83 ng/mL, respectively.
"
Related Drugs and Biologics
1.
Fluorouracil (Carac)