|1.||Wu, Ting-Feng: 2 articles (07/2015 - 12/2011)|
|2.||Rehman, Ishtiaq: 2 articles (05/2014 - 01/2013)|
|3.||McCleland, Mark L: 2 articles (02/2013 - 11/2012)|
|4.||Adler, Adam S: 2 articles (02/2013 - 11/2012)|
|5.||Firestein, Ron: 2 articles (02/2013 - 11/2012)|
|6.||Li, Li: 2 articles (02/2013 - 11/2012)|
|7.||Blackwood, Elizabeth M: 2 articles (02/2013 - 11/2012)|
|8.||Sivridis, Efthimios: 2 articles (11/2012 - 01/2006)|
|9.||Koukourakis, Michael I: 2 articles (11/2012 - 01/2006)|
|10.||Giatromanolaki, Alexandra: 2 articles (11/2012 - 01/2006)|
|1.||Non-Hodgkin Lymphoma (Lymphosarcoma)
01/01/1984 - "In non-Hodgkin lymphoma (NHL) a diminution in LDH1 and an increase in LDH2 was a sign of evolution towards a more aggressive phase of the disease, or the absence of clinical remission, even when no significant variation of total LDH can be observed in the serum. "
02/01/2004 - "Based on the possibility of tumor necrosis factor (TNF)-alpha to perform multiple and opposite biologic effects, we simultaneously investigated in vitro its effects on intracellular lactate dehydrogenase (LDH)-H and LDH-M isoenzyme activity and morphological characteristics following induction of apoptosis in peripheral blood mononuclear cells (PBMC) of non-Hodgkin's lymphoma patients (NHL) prior to and after the end of applied chemotherapy. "
08/01/1979 - "The authors' study showed that the maximum indices of the activity of LDH, LDH1 fraction and CPK in blood serum were higher in patients with severe myocardial infarction than in those with a mild course of the disease. "
07/01/1983 - "An examination of 400 coronary patients demonstrated a relationship between increased serum CPK, AST, LDH and LDH-1, and the spread and severity of myocardial infarction (MI). "
07/01/1981 - "There was no significant change in the LDH1 at any time after myocardial infarction. "
05/01/1981 - "The immunochemical method for LDH-1 is more sensitive than electrophoresis for the detection of myocardial infarction and offers the further advantages of greater simplicity, precision, and accuracy, while being no less specific."
05/01/1981 - "Ten (40%) of the 25 samples collected at the time of admission from 25 patients who had myocardial infarctions had elevated LDH-1 activity by electrophoresis, while 14 patients (56%) had increased LDH-1 by immunochemistry. "
09/01/2015 - "Lactate dehydrogenase B (LDHB) is widely expressed in adult somatic tissue and plays important roles in the development of human cancers. "
01/20/2015 - "Over-expression of LDH-B in cancer cell lines leads to enhanced apoptosis, mitochondrial damage, and reduced cell migration. "
05/01/2014 - "This effect was probably related to the absence of the LDH-B subunit in LNCaP-LN3 cells, and could have a bearing on cancer treatment with DCA and related compounds."
01/01/2013 - "Histopathologic data from the treated tumors showed higher cellular apoptosis and senescence; and changes in the expression of membrane monocarboxylate transporters and lactate dehydrogenase B were also observed. "
01/01/2013 - "Lactate dehydrogenase-B is silenced by promoter methylation in a high frequency of human breast cancers."
06/01/2010 - "Our results suggest that the three LDH1 variants might play an important role in the adaptation to hypoxia."
09/01/2009 - "heteroclitus Ldh-B promoter confers hypoxia-dependence upon reporter gene expression in transiently transfected mammalian (Hep3B) and fish (RTG-2 and RTH-149) cells in culture. "
09/01/2009 - "A novel hypoxia-response element in the lactate dehydrogenase-B gene of the killifish Fundulus heteroclitus."
05/01/2003 - "Furthermore, chronic hypoxia limits LDH B gene transcription or its mRNA stability in both soleus and EDL. "
06/01/2001 - "Structure and sequence conservation of a putative hypoxia response element in the lactate dehydrogenase-B gene of Fundulus."
12/01/2011 - "Loss of lactate dehydrogenase B subunit expression is correlated with tumour progression and independently predicts inferior disease-specific survival in urinary bladder urothelial carcinoma."
01/01/1985 - "The prostatic fluid LDH5/LDH1 ratio and PHI has been found to be the most sensitive parameter for detecting carcinoma prostate. "
04/01/1994 - "Levels in the nipple discharge of patients with breast cancer, including noninvasive carcinoma, tended to increase in ascending order from LDH1 to LDH5. "
04/01/1983 - "LDH isozyme ratio (LDH4 + LDH5/LDH1 + LDH2) and H subunit % (LDH1 + 3/4LDH2 + 1/2LDH5 + 1/4LDH) in cancer tissue were obviously different from those of control materials, LDH isozyme ratio in normal tissue within 4 cm from the edge of carcinoma and H subunit % within 6 cm showed the significant difference to those in control materials. "
04/15/1980 - "A consistent and definite shift of the LDH5 : LDH1 ratio has been found in carcinomas respect to benign hyperplasias."
|1.||lactate dehydrogenase 1 (LDH1)
|2.||L-Lactate Dehydrogenase (Lactate Dehydrogenase)
|4.||lactate dehydrogenase 5
|6.||Aspartate Aminotransferases (Aspartate Transaminase)
|7.||lactate dehydrogenase 2
|8.||MB Form Creatine Kinase
|10.||Glycogen Phosphorylase (Phosphorylase, Glycogen)
|1.||Drug Therapy (Chemotherapy)
|3.||Induced Heart Arrest (Cardioplegia)
|4.||Electric Countershock (Cardioversion)