alpha chain CD8 antigen

Also Known As:

CD8 antigen, alpha chain; CD8 alphaalpha antigen; CD8 antigen, alpha chain, mouse; CD8 antigen, alpha chain, rat; CD8 antigen, alpha polypeptide p32; CD8 antigen, alpha polypeptide p32, human; CD8A protein, human; CD8a molecule protein, human; CD8alphaalpha antigen; Cd8a antigen; Cd8a protein, mouse; Cd8a protein, rat; Ly-2 antigen, mouse; Ly-35 antigen, mouse; Ly-B antigen, mouse; T-cell surface glycoprotein CD8 alpha chain; wt CD8

Networked: 7 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Biological Factors: 2472
- Biomarkers: 240291
  - Differentiation Antigens: 2082
    - T-Lymphocyte Differentiation Antigens: 40
      - CD8 Antigens: 99
        alpha chain CD8 antigen: 7
- Antigens: 143924
  - Surface Antigens: 5813
    - Differentiation Antigens: 2082
      - T-Lymphocyte Differentiation Antigens: 40
        CD8 Antigens: 99
        alpha chain CD8 antigen: 7

Experts

1.	Henderson, Kyle K: 1 article (10/2015)
2.	Manam, Srikanth: 1 article (10/2015)
3.	Murthy, Ashlesh K: 1 article (10/2015)
4.	Ramsey, Kyle H: 1 article (10/2015)
5.	Zafiratos, Mark T: 1 article (10/2015)
6.	Ali, Asim Q: 1 article (08/2011)
7.	Ballard, Billy: 1 article (08/2011)
8.	Fang, Rong: 1 article (08/2011)
9.	Forbes, Digna: 1 article (08/2011)
10.	Ghose, Purnima: 1 article (08/2011)

Related Diseases

1.	Neoplasms (Cancer) 11/15/2009 - "In vitro studies indicate that optimally activated OVA-specific TNFR2(-/-) CD8 T cells proliferated to the same extent and possess similar cytotoxicity against E.G7 tumor cells as WT CD8 T cells. "
2.	Infections 08/01/2011 - "Adoptive transfer of immune WT CD8(+) T cells increased bacterial burden in IL-18Rα(-/-) mice following IOE infection. " 10/29/2007 - "Interestingly, infected TAP-1(-/-) mice also showed reduced numbers of IFN-gamma-producing natural killer (NK) cells relative to WT, CD8(-/-), or beta(2)m(-/-) mice, and after NK cell depletion both CD8(-/-) and WT mice succumbed to infection with the same kinetics as TAP-1(-/-) animals and displayed impaired CD4(+) T cell IFN-gamma responses. " 02/01/2004 - "While wt CD8(+) T cells inhibited virus replication in all CNS cell types, cytolytic activity in the absence of IFN-gamma suppressed the infection of astrocytes, but not oligodendroglia. " 12/01/2000 - "Depletion of CD8(+) T cells in ss7(-/-) animals prolonged viral shedding, and transfer of immune ss7(-/-) CD8(+) T cells into chronically infected Rag-2-deficient mice resolved RV infection as efficiently as wt CD8(+) T cells. " 10/01/2015 - "Moreover, repletion of CD8 KO mice with WT CD8(+) T cells (1 × 10(7) cells/mouse intravenously) at the time of infection reverted atherosclerotic plaque lesions to WT levels. "
3.	Atherosclerotic Plaque (Atheroma) 10/01/2015 - "Moreover, repletion of CD8 KO mice with WT CD8(+) T cells (1 × 10(7) cells/mouse intravenously) at the time of infection reverted atherosclerotic plaque lesions to WT levels. "
4.	Demyelinating Diseases (Demyelinating Disease) 02/01/2004 - "Demyelination was most severe following viral control by wt CD8(+) T cells but was independent of macrophage infiltration. "

Related Drugs and Biologics

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