4-boronic acid benzophenone

07/01/1998 - "BBP women reported significantly greater worry about breast cancer than HC women. "
10/01/2018 - "Findings from this study could provide an important new perspective on the molecular mechanisms through which BBP exerts its promoting effect on breast cancer as well as its target intervention."
11/01/2023 - "Evaluating the potential impact of BBP and PFOA exposure on pubertal breast density is important to our understanding of early-life environmental influences on breast cancer etiology. "
12/01/2015 - "In addition, BBP also stimulated the production of CXCL1/GROα by TADCs, which increased the angiogenesis of breast cancer in a mouse model. "
01/01/2011 - "We analyzed a total of 38 women diagnosed with breast cancer and 95 women diagnosed with a BBP. "

09/01/2016 - "We assessed the tolerability and efficacy of PB as BBP in Japanese patients with metastatic colorectal cancer (mCRC). "
01/01/2012 - "This trial evaluates the efficacy and safety of BBP for patients with metastatic colorectal cancer that progressed on first-line chemotherapy. "
09/19/2019 - "BBP has been proven to prolong overall survival (OS) in recurrent colorectal cancer and progression-free survival (PFS) in recurrent breast and lung cancers. "
10/29/2021 - "The ML18174 study, which showed benefits of bevacizumab (BEV) continuation beyond progression (BBP) for metastatic colorectal cancer (mCRC), excluded patients with first-line progression-free survival (PFS) shorter than 3 months. "
08/01/2014 - "Additionally, the ML18147 trial demonstrated that bevacizumab beyond progression(BBP)prolonged overall survival(OS)and progression free survival(PFS)in patients with advanced colorectal cancer. "

02/01/2014 - "A significant reduction in dams' body weight on GD21 in DBP-, BBP-, and DES-treated groups was observed. "
03/01/2003 - "There is no direct evidence that exposure of people to BBP adversely affects reproduction or development, but studies reviewed by the expert panel show that oral exposure of laboratory animals to high doses (>/=1000 mg/kg body weight/day) of BBP can adversely affect development, including development of the male reproductive tract. "
01/01/2022 - "C57Bl/6 male and female mice were fed either a chow diet (CD) or HFD with or without BBP (3 mg/kg body weight/day)and/or PQQ (20 mg/kg/day)for 16 weeks. "
07/01/2020 - "Male mice exposed to moderate (3 mg/kg bw/day) concentrations of BBP in an HFD were especially affected, with significant increases in body weight due to significant increases in weight of liver and adipose tissue. "
02/01/2014 - "Decline in male pups' body weight was significant at PND75 in DBP- (50 mg/kg), BBP- (20,100 mg/kg), and DES-treated groups. "

02/01/2014 - "BBP may be a potential novel therapeutic agent for the treatment of hepatocellular carcinoma."
08/01/2014 - "BBP could induce the apoptosis of hepatoma carcinoma cells and inhibit their proliferation by regulating STAT3 pathway."
08/01/2014 - "Results of TUNEL showed that BBP could significantly induce the apoptosis of hepatoma carcinoma cells. "
05/01/2020 - "To evaluate the inhibitory effect of bear bile powder (BBP) on hepatocellular carcinoma (HCC) growth in vivo and investigate the underlying mechanisms. "
08/01/2014 - "To observe the effect of bear bile powder (BBP) on the STAT3 pathway and its downstream target genes of nude mice hepatocellular carcinoma (HCC) xenograft, and to explore its mechanism for treating HCC. "

07/01/2014 - "In addition to support findings from previous studies, a modified intent-to-treat (mITT) analysis compared PPS in patients who received bevacizumab beyond disease progression (BBP) with those who did not (No-BBP). "
11/20/2008 - "The 1,445 of 1,953 previously untreated patients with mCRC who were enrolled in BRiTE and who experienced disease progression (PD) were classified into three groups: no post-PD treatment (n = 253), post-PD treatment without bevacizumab (no BBP; n = 531), and BBP (n = 642). "
01/01/2016 - "This analysis from the ARIES observational cohort study (OCS) was initiated to evaluate the effect of bevacizumab use beyond disease progression (BBP) on clinical outcomes in patients with NSCLC receiving first-line treatment with bevacizumab and chemotherapy. "