|1.||Behrendt, Niels: 5 articles (10/2015 - 06/2005)|
|2.||Engelholm, Lars H: 5 articles (10/2015 - 06/2005)|
|3.||Sturge, Justin: 5 articles (03/2015 - 11/2007)|
|4.||Madsen, Daniel H: 4 articles (10/2015 - 04/2007)|
|5.||Waxman, Jonathan: 4 articles (03/2015 - 03/2009)|
|6.||Bugge, Thomas H: 4 articles (05/2012 - 06/2005)|
|7.||Isacke, Clare M: 4 articles (01/2010 - 04/2002)|
|8.||Rodriguez-Teja, Mercedes: 3 articles (03/2015 - 04/2012)|
|9.||Mauri, Francesco: 3 articles (03/2015 - 04/2012)|
|10.||Gronau, Julian H: 3 articles (03/2015 - 04/2012)|
|1.||Prostatic Neoplasms (Prostate Cancer)
03/01/2015 - "This study identifies the interaction between CTLD4 in Endo180 and CD147 as an EMT suppressor and indicates that stabilization of this molecular complex improves prostate cancer survival rates."
03/01/2015 - "This study provides a rationale for targeting CTLD2 in Endo180 in prostate cancer and other pathologies in which increased basal lamina thickness and tissue stiffness are driving factors. "
03/01/2015 - "AGE-modified basement membrane cooperates with Endo180 to promote epithelial cell invasiveness and decrease prostate cancer survival."
03/01/2015 - "Here, the multi-CTLD mannose receptor, Endo180 (MRC2/uPARAP), was shown using the Kaplan-Meier analysis to be predictive of survival outcome in men with early prostate cancer. "
03/01/2015 - "Our in vitro results were concordant with luminal occlusion of acini in the prostate glands of adult Endo180(Δ) (Ex2-6/) (Δ) (Ex2-6) mice, with constitutively exposed CTLD2 and decreased survival of men with early (non-invasive) prostate cancer with high epithelial Endo180 expression and levels of AGE. "
10/01/2015 - "With a particular focus on matrix turnover in cancer, this review presents the necessary background for understanding the function of uPARAP/Endo180 at the molecular and cellular level, followed by an in-depth survey of the available knowledge of the expression and role of this receptor in various types of cancer and other degenerative diseases."
10/01/2015 - "Important pathological functions of uPARAP/Endo180 have been identified in various cancers and in several fibrotic conditions. "
11/01/2007 - "Second, a proportion of Endo180(+) tumors were shown to have Endo180 gene copy number gains and amplifications. "
11/01/2007 - "Here, we show that high levels of Endo180 are found in a subset of basal-like breast cancers and that this expression is an independent prognostic marker for shorter disease-free survival. "
11/01/2007 - "The contrary observation that Endo180 is expressed on epithelial tumor cell lines that display a high invasive capacity suggested that up-regulation of this receptor may be an associated and functional component in the acquisition of a more aggressive phenotype by tumor cells in vivo. "
|3.||Neoplasm Metastasis (Metastasis)
01/15/2013 - "Bisphosphonate treatment was associated with reduced Endo180 levels in BCa patients with bone metastasis (P=0.011; n=42). "
04/01/2012 - "Immunohistochemical analysis of core biopsies from bone metastasis revealed higher levels of Endo180 expression in tumour cell foci than cells in the surrounding stroma. "
01/15/2013 - "Here, we confirm the release and diagnostic accuracy of soluble Endo180 for diagnosing metastasis in breast cancer (BCa). "
04/01/2012 - "The findings of this study provide a rationale for targeting collagen remodelling by Endo180 in bone metastases and other collagen matrix pathologies."
01/15/2013 - "True/false-positive rates for metastasis classification were: 85%/50% for the reference standard, CA 15-3 antigen (28 U ml(-1)); ≤97%/≥36% for Endo180; and ≤97%/≥32% for CA 15-3 antigen+Endo180. "
|4.||Wounds and Injuries (Trauma)
12/01/2006 - "The aim of this study was to examine the expression of Endo180 during gingival wound regeneration. "
12/01/2006 - "The findings suggest that Endo180 plays a role in re-epithelialization and connective tissue remodelling during wound regeneration."
12/01/2006 - "In wounds, Endo180 expression was spatiotemporally increased in the migrating and differentiating wound epithelium, in subsets of myofibroblasts, pericytes, macrophages and endothelial cells. "
01/01/2010 - "Further, interrogation of multiple expression array datasets identified Endo180 as one of the most highly upregulated transcripts in grade IV GBMs compared to grade III gliomas. "
01/01/2010 - "Together these data provide important insights into the mechanism of GBM invasion and identify Endo180 as a potential target to limit matrix turnover by glioma cells and thereby restrict tumor progression."
01/01/2010 - "A role for fibrillar collagen deposition and the collagen internalization receptor endo180 in glioma invasion."
06/01/2011 - "To identify molecular therapeutic targets for glioma, we performed gene expression profiling by using a complementary DNA (cDNA) microarray method and identified the urokinase plasminogen activator receptor-associated protein (uPARAP/Endo180) as a gene expressed highly in glioma tissue compared with the normal brain tissue. "
|4.||Matrix Metalloproteinase 14 (MT1-MMP)
|5.||Urokinase-Type Plasminogen Activator (Urokinase)
|6.||Plasminogen Activators (Plasminogen Activator)
|8.||mannose receptor (receptor, mannose)
|9.||G-Protein-Coupled Receptors (Receptors, G Protein Coupled)
|10.||Mucin-1 (CA 15-3 Antigen)