|1.||Hisadome, Masao: 4 articles (07/2006 - 08/2004)|
|2.||Fukuda, Tetsuko: 4 articles (07/2006 - 08/2004)|
|3.||Komatsu, Hirotsugu: 4 articles (07/2006 - 08/2004)|
|4.||Uemura, Masahito: 2 articles (04/2011 - 11/2009)|
|5.||Fukui, Hiroshi: 2 articles (04/2011 - 11/2009)|
|6.||Tsujimoto, Tatsuhiro: 2 articles (04/2011 - 11/2009)|
|7.||Kawaratani, Hideto: 2 articles (04/2011 - 11/2009)|
|8.||Yoshiji, Hitoshi: 2 articles (04/2011 - 11/2009)|
|9.||Kitazawa, Toshiyuki: 2 articles (04/2011 - 11/2009)|
|10.||Mogami, Akira: 2 articles (07/2006 - 10/2005)|
07/24/2006 - "In the present study, we examined the effect of Y-40138 on D-GalN/LPS-induced hepatitis. "
07/24/2006 - "Y-40138, a multiple cytokine production modulator, protects against D-galactosamine and lipopolysaccharide-induced hepatitis."
10/31/2005 - "Therapeutic administration of Y-40138, a multiple cytokine modulator, inhibits concanavalin A-induced hepatitis in mice."
07/24/2006 - "Y-40138 suppressed plasma alanine transaminase (ALT) elevation and improved survival rate in D-GalN/LPS-injected mice, and it is suggested that the protective effect of Y-40138 on hepatitis may be mediated by inhibition of TNF-alpha and MCP-1, and/or augmentation of IL-10. "
10/31/2005 - "In this study, we compared the effect of Y-40138 with those of pentoxifylline and anti-TNF-alpha antibody on concanavalin A-induced hepatitis. "
08/30/2004 - "These data suggest that combined treatment with Y-40138 and methotrexate may increase efficacy of therapy for rheumatoid arthritis."
03/17/2000 - "The finding that Y-39041 suppresses TNF-alpha production and stimulates interleukin-10 production at the same time provides new insights for the treatment of septic shock, rheumatoid arthritis and Crohn's diseases."
|3.||Alcoholic Liver Diseases (Alcoholic Liver Disease)
04/01/2011 - "Therapeutic effects of cytokine modulator Y-40138 in the rat alcoholic liver disease model."
10/31/2005 - "From these results, Y-40138 may be expected as a new class of therapeutic drug for treatment of TNF-alpha, IFN-gamma and/or chemokine-related liver diseases such as alcoholic liver disease."
|1.||Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
|2.||Interleukin-10 (Interleukin 10)
|4.||Alanine Transaminase (SGPT)