|1.||Beckmann, Matthias W: 8 articles (01/2013 - 01/2007)|
|2.||Strissel, Pamela L: 8 articles (01/2013 - 01/2007)|
|3.||Strick, Reiner: 8 articles (01/2013 - 01/2007)|
|4.||Li, Jinping: 5 articles (01/2015 - 01/2014)|
|5.||Jiang, Shi-Wen: 5 articles (01/2015 - 01/2014)|
|6.||Dolei, Antonina: 5 articles (11/2014 - 04/2005)|
|7.||Larsson, Lars-Inge: 5 articles (08/2012 - 01/2007)|
|8.||Mameli, Giuseppe: 4 articles (11/2014 - 05/2007)|
|9.||Serra, Caterina: 4 articles (11/2014 - 05/2007)|
|10.||Ruebner, Matthias: 4 articles (01/2013 - 11/2010)|
11/01/2001 - "Here we present the first evidence that in pre-eclampsia, syncytin gene expression levels are dramatically reduced. "
02/01/2006 - "The quantitative real-time polymerase chain reaction was used to study the syncytin and ASCT2 expression during placental development in 35 placentas from women without pre-eclampsia (ranged from 5 to 40 weeks of gestation) and the alterations of pre-eclamptic placentas (n=16) compared with gestational-age-matched controls (n=16). "
11/01/2001 - "The present study suggests that altered expression of the syncytin gene, and altered cellular location of its protein product, may contribute to the aetiology of pre-eclampsia."
11/01/2014 - "These various aspects of the implication of Syncytin-1 and -2 in placental function are also addressed in the context of the placenta-related disorder, preeclampsia."
01/01/2014 - "These results indicated that aberrant hypermethylation is involved in downregulation of syncytin-1, and epigenetic alterations may play a significant role in the development of preeclampsia. "
08/01/2003 - "The purpose of this study was to test the hypothesis that hypoxia down-regulates placental syncytin, which could play a role in altered placentogenesis; we investigated the influence of hypoxia on syncytin and its receptor ASCT2 gene expression in BeWo cells and in ex vivo perfused human cotyledons. "
01/01/2009 - "Severe hypoxia is associated with reduced GCMa and syncytin-1 transcripts and altered fusion of primary trophoblasts."
01/01/2009 - "We investigated how different levels of hypoxia alter the expression of syncytin-1, glial cells missing a (GCMa) and syncytin-1 receptor ASCT2 and affect syncytialization in primary term human trophoblasts. "
01/01/2009 - "Syncytin-1 and glial cells missing a: hypoxia-induced deregulated gene expression along with disordered cell fusion in primary term human trophoblasts."
02/01/2006 - "Correspondingly, hypoxia decreases syncytin but not ASCT2 gene expression in cultured cytotrophoblasts."
07/01/2006 - "This study confirms that syncytin is expressed widely by a variety of normal human trophoblast populations, as well as choriocarcinoma cell lines."
08/01/2012 - "Analysis of heterotypic fusion activity between trophoblast-derived choriocarcinoma BeWo cells, in which syncytin-1 and envPb1 are specifically silenced, and endothelial cells demonstrated that both syncytin-1 and envPb1 are important to fusion. "
07/01/2006 - "Syncytin transcripts were found in first-trimester trophoblast cells with both villous and extravillous phenotypes and also in the JAR and JEG-3 choriocarcinoma cell lines. "
04/15/2006 - "Hypomethylation of the syncytin-1 5' long terminal repeat in the placenta and in the choriocarcinoma-derived cell line BeWo was detected. "
08/01/2014 - "Reduced syncytin-1 expression in choriocarcinoma BeWo cells activates the calpain1-AIF-mediated apoptosis, implication for preeclampsia."
01/01/2015 - "In this study, applying the real-time PCR, Western blot analysis and immunohistochemistry methods, we demonstrate a constitutive expression of syncytin-1 in normal pancreas tissues as well as normal tissues adjacent to cancer lesions. "
03/01/2014 - "The functions of syncytiotrophoblasts, the fusogenic and non-fusogenic activities of syncytin-1, and aberrant activation of syncytin-1 expression in cancer cells are also discussed. "
03/01/2014 - "Epigenetic and non-epigenetic regulation of syncytin-1 expression in human placenta and cancer tissues."
10/01/2013 - "These results suggest that syncytin expression in some cancers may confine their invasion potential and thus serve as a positive prognostic factor."
10/01/2013 - "The effect of syncytin on the invasion potential of tumor cells was evaluated in B16F10 subline cells that stably expressed syncytin-EGFP fusion protein or EGFP alone. "
11/28/2014 - "The objective of this study is to verify whether HIV activates two endogenous retroviruses of the human endogenous retrovirus (HERV)-W family, multiple sclerosis-associated retrovirus (MSRV) and Syncytin-1, whose neuropathogenic and immunopathogenic properties could contribute to HIV-related neurodegeneration. "
12/01/2013 - "Deregulated HERV-W expression and HERV-W locus ERVWE1-encoded Syncytin-1 protein have been implicated in the pathogenesis of multiple sclerosis (MS). "
07/15/2007 - "The human endogenous retrovirus (HERV-W) envelope protein, Syncytin-1, is highly expressed in CNS glia of individuals with multiple sclerosis (MS). "
04/01/2005 - "MSRV/HERV-W/syncytin and its linkage to multiple sclerosis: the usability and the hazard of a human endogenous retrovirus."
04/01/2014 - "Whereas syncytin-1 appears to be crucial for the development and functioning of the human placenta, its ectopic expression has been associated with pathological conditions, such as multiple sclerosis and schizophrenia. "
|1.||Messenger RNA (mRNA)
|2.||Small Interfering RNA (siRNA)
|4.||RNA (Ribonucleic Acid)
|5.||Proteins (Proteins, Gene)
|9.||Transcription Factor 7-Like 2 Protein
|1.||Heterologous Transplantation (Xenotransplantation)