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vatalanib (PTK787)

blocks vascular endothelial growth factor (VEGF) receptor signaling
Also Known As:
PTK787; ZK 222584; 1-(4-chloroanilino)-(4-pyridylmethyl)phthalazine dihydrochloride; 1-(4-chloroanilino)-4-(pyridylmethyl)phthalazine; 1-(4-chloroanilino)-4-(pyridylmethyl)phthalazine dihydrochloride; CGP 797870; CGP-797870; PTK 787; PTK-787; ZK 232934; ZK-222584; ZK-232934; ZK222584; ZK232934
Networked: 158 relevant articles (16 outcomes, 71 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Wood, Jeanette: 11 articles (12/2014 - 07/2002)
2. Laurent, Dirk: 10 articles (04/2014 - 11/2003)
3. Arbab, Ali S: 7 articles (10/2018 - 01/2010)
4. Wood, J: 7 articles (04/2005 - 03/2000)
5. Laurent, D: 6 articles (09/2012 - 04/2005)
6. Morgan, Bruno: 5 articles (04/2014 - 11/2003)
7. Lebwohl, David: 5 articles (07/2011 - 06/2006)
8. Drevs, Joachim: 5 articles (06/2010 - 07/2002)
9. Schnell, Christian: 5 articles (03/2008 - 03/2004)
10. Prous, J R: 5 articles (04/2007 - 01/2003)

Related Diseases

1. Neoplasms (Cancer)
2. Colorectal Neoplasms (Colorectal Cancer)
3. Glioma (Gliomas)
4. Hepatocellular Carcinoma (Hepatoma)
5. Melanoma (Melanoma, Malignant)

Related Drugs and Biologics

1. vatalanib (PTK787)
2. Vascular Endothelial Growth Factor Receptors (VEGF Receptors)
3. Tyrosine Kinase Inhibitors
4. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
5. Imatinib Mesylate (Gleevec)
6. Sunitinib (Sutent)
7. Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)
8. Phosphotransferases (Kinase)
9. Biomarkers (Surrogate Marker)
10. Tyrosine (L-Tyrosine)

Related Therapies and Procedures

1. Therapeutics
2. Oral Administration
3. Drug Therapy (Chemotherapy)
4. Stents
5. Radiotherapy