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SC 58560

a COX-1 inhibitor; no further information available 3/00

Also Known As:

SC-58560; SC58560

Networked: 4 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- SC 58560: 4

Experts

1.	Menuki, Kunitaka: 1 article (01/2008)
2.	Nakai, Kenichiro: 1 article (01/2008)
3.	Nakamura, Toshitaka: 1 article (01/2008)
4.	Sakai, Akinori: 1 article (01/2008)
5.	Taketa, Tomonori: 1 article (01/2008)
6.	Tanaka, Kazuhiro: 1 article (01/2008)
7.	Tanaka, Shinya: 1 article (01/2008)
8.	Yamane, Hirotoshi: 1 article (01/2008)
9.	Christman, John W: 1 article (04/2002)
10.	Collins, Robert D: 1 article (04/2002)

Related Diseases

1.	Respiratory Hypersensitivity 04/15/2002 - "Ovalbumin-sensitized mice treated with either selective COX-1 inhibitor SC58560 (OVA-COX-1 inhibitor) or selective COX-2 inhibitor SC58236 (OVA-COX-2 inhibitor) had significantly greater airway hyperresponsiveness (p < 0.05) and higher levels of IL-13 (p < 0.05) in lung supernatants than did untreated mice that were ovalbumin sensitized (OVA). "
2.	Neoplasms (Cancer) 01/01/2001 - "We have used colonic carcinoma and adenoma cell lines to study the effects of the NSAID sulindac sulfide, its COX-inactive metabolite, sulindac sulfone, and the isoenzyme-specific inhibitors SC58125, SC236 and SC58560 on tumor cell growth in relation to COX-2 expression and prostaglandin production. "
3.	Carcinoma (Carcinomatosis) 01/01/2001 - "We have used colonic carcinoma and adenoma cell lines to study the effects of the NSAID sulindac sulfide, its COX-inactive metabolite, sulindac sulfone, and the isoenzyme-specific inhibitors SC58125, SC236 and SC58560 on tumor cell growth in relation to COX-2 expression and prostaglandin production. "
4.	Bone Resorption 01/01/2008 - "We performed this study to clarify whether celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, prevents trabecular bone mass reduction by suppressing arthritis-related increase of bone resorption, and to discriminate differences in actions on bone among celecoxib, SC-58560 (a selective COX-1 inhibitor), and indomethacin. "
5.	Arthritis (Polyarthritis) 01/01/2008 - "We performed this study to clarify whether celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, prevents trabecular bone mass reduction by suppressing arthritis-related increase of bone resorption, and to discriminate differences in actions on bone among celecoxib, SC-58560 (a selective COX-1 inhibitor), and indomethacin. "

Related Drugs and Biologics

1.	4- (5- (4- chlorophenyl)- 3- (trifluoromethyl)- 1H- pyrazol- 1- yl)benzenesulfonamide
2.	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)
3.	Interleukin-13
4.	Ovalbumin
5.	Cyclooxygenase 2 (Cyclooxygenase-2)
6.	Prostaglandins
7.	Isoenzymes
8.	Indomethacin (Indometacin)
9.	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)
10.	Celecoxib (Celebrex)