iodomethyl-N,N-diethyltamoxifen
a receptor radioligand
Networked: 3
relevant articles (1 outcomes,
2 trials/studies)
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Bio-Agent Context: Research Results
Experts
Related Diseases
| 1. | Breast Neoplasms (Breast Cancer)
04/01/2001
- " A high-performance liquid chromatographic procedure for the quantitation of [(123)I]Iodomethyl-N,N-diethyltamoxifen (ITX), a radioligand for human breast cancer imaging, in human plasma is described. " 07/01/1992
- " In studies of human MCF7 breast tumor cell growth, concentrations that inhibited tumor growth in 50% of the cases were as follows: tamoxifen, 11 microM; fluoromethyl-N,N-diethyltamoxifen, 4.5 and 11.8 microM for the cis and trans isomers, respectively; and iodomethyl-N,N-diethyltamoxifen, 2.4 and 6.3 microM for the cis and trans isomers, respectively. " 10/01/1999
- " This study reports on the distribution and radiation dosimetry of iodine-123 labelled trans-Z-iodomethyl-N,N-diethyltamoxifen (123-ITX), a promising radioligand for prediction of the therapeutic efficacy of unlabelled tamoxifen in human breast carcinoma. "
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| 2. | Neoplasms (Cancer)
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