HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

Nogo protein

a neurite growth inhibitor restricting the structural plasticity and regeneration of nerve fibers in the adult vertebrate CNS; Nogo-66 refers to the 66-residue extracellular domain; has been sequenced
Also Known As:
ASY protein, human; NI-220 protein; NI-250 protein; NI-35 protein; NI-35-250; Nogo protein, human; Nogo protein, mouse; Nogo protein, rat; Nogo-66 protein; Nogo-A protein; Nogo-B protein; Nogo-C protein; Nogo66 protein, rat; Nogo66 protein, zebrafish; RTN-x protein, human; RTN4 protein, human; Rtn4 protein, Xenopus; Rtn4 protein, mouse; Rtn4 protein, rat; endoplasmic reticulum protein 22, rat; neurite growth inhibitor 35-350; reticulon 4 protein, human; reticulon 4 protein, mouse; reticulon 4 protein, rat; reticulon 4-B; reticulon-4; vp20 protein, rat
Networked: 24 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Sehgal, Pravin B: 3 articles (10/2013 - 03/2012)
2. Yang, Yang-Ming: 2 articles (02/2013 - 03/2012)
3. Lee, Jason E: 2 articles (02/2013 - 03/2012)
4. Ma, Yong: 1 article (02/2015)
5. Hua, Zhen: 1 article (02/2015)
6. Wang, Jian-Wei: 1 article (02/2015)
7. Yang, Jun-Feng: 1 article (02/2015)
8. Guo, Yang: 1 article (02/2015)
9. Zhang, Ya-Feng: 1 article (02/2015)
10. Gu, Xiao-Lin: 1 article (02/2015)

Related Diseases

1. Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
2. Spinal Cord Injuries (Spinal Cord Injury)
3. Cysts
03/01/2012 - "Acute knockdown of STAT5a/b species using small interfering RNAs (siRNAs), including in the presence of an mRNA synthesis inhibitor (5,6-dichloro-1-β-d-ribofuranosylbenzimidazole), produced a dramatic phenotype within 1 day, consisting of dilatation and fragmentation of Golgi cisternae, a marked tubule-to-cyst change in the ER, increased accumulation of reticulon-4 (RTN4)/Nogo-B and atlastin-3 (ATL3) at cyst-zone boundaries, cystic separation of the outer and inner nuclear membranes, accompanied by scalloped/lunate distortion of the nucleus, with accumulation of RTN4 on convex sides of distorted nuclei. "
10/01/2013 - "Acute siRNA-mediated knockdown of STAT5A/B led to the rapid development of a dramatic cystic change in the endoplasmic reticulum (ER) characterized by deposition of the ER structural protein reticulon-4 (RTN4; also called Nogo-B) and the ER-resident GTPase atlastin-3 (ATL3) along cyst membranes and cyst-zone boundaries, accompanied by Golgi fragmentation. "
02/15/2013 - "In a novel line of research in human pulmonary arterial endothelial cells (HPAECs), we previously observed that STAT5a associated with the Golgi apparatus and that siRNA-mediated knockdown of STAT5a/b led to the rapid development of a dramatic cystic change in the endoplasmic reticulum (ER) characterized by deposition along cyst membranes and tubule-to-cyst boundaries of the proteins reticulon-4 (RTN4; also called Nogo-B) and the ER-resident GTPase atlastin-3 (ATL3) and Golgi fragmentation. "
4. Stroke (Strokes)
5. Neoplasms (Cancer)

Related Drugs and Biologics

1. Messenger RNA (mRNA)
2. Small Interfering RNA (siRNA)
3. GTP Phosphohydrolases (GTPases)
4. Glial Fibrillary Acidic Protein
5. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
6. GAP-43 Protein (GAP 43 Protein)
7. Myelin-Associated Glycoprotein (S-MAG)
8. Neurotransmitter Receptors (Neurotransmitter Receptor)
9. Proteins (Proteins, Gene)
10. Phosphotransferases (Kinase)