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integrin alphavbeta8

a novel growth-regulatory molecule of epithelial cells

Also Known As:

alphavbeta8 integrin

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - Immunologic Receptors: 9
        Integrins: 14304
        integrin alphavbeta8: 7

Experts

1.	Cambier, Stephanie: 2 articles (02/2010 - 05/2004)
2.	Nishimura, Stephen L: 2 articles (02/2010 - 08/2006)
3.	Aldape, K D: 1 article (08/2010)
4.	Hossain, M G: 1 article (08/2010)
5.	McCarty, J H: 1 article (08/2010)
6.	Mobley, A K: 1 article (08/2010)
7.	Tchaicha, J H: 1 article (08/2010)
8.	Bollen, Andrew W: 1 article (02/2010)
9.	Kim, Helen: 1 article (02/2010)
10.	Kitamura, Hideya: 1 article (02/2010)

Related Diseases

1.	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/01/2008 - "Dendritic cells, TGF-beta, and Integrin alphavbeta8 in inflammatory bowel disease: a tolerogenic "ménage à trois"."
2.	Wounds and Injuries (Trauma) 08/01/2006 - "Activation of transforming growth factor-beta by the integrin alphavbeta8 delays epithelial wound closure."
3.	Pathologic Neovascularization 08/05/2010 - "Using mosaic mouse models of the malignant brain cancer, astrocytoma, we report that tumor cells induce pathological angiogenesis by suppressing expression of the ECM protein receptor alphavbeta8 integrin. "
4.	Neoplasms (Cancer) 08/05/2010 - "A mosaic mouse model of astrocytoma identifies alphavbeta8 integrin as a negative regulator of tumor angiogenesis." 08/05/2010 - "Using mosaic mouse models of the malignant brain cancer, astrocytoma, we report that tumor cells induce pathological angiogenesis by suppressing expression of the ECM protein receptor alphavbeta8 integrin. "
5.	Lung Neoplasms (Lung Cancer) 12/15/2000 - "On the basis of our findings that the integrin beta8 subunit is expressed in airway epithelial cells and is absent in lung cancers, we investigated the role and mechanism of the integrin alphavbeta8 in mediating growth inhibition. "

Related Drugs and Biologics

1.	Transforming Growth Factor beta (TGF-beta)
2.	Integrins
3.	Proteins (Proteins, Gene)
4.	integrin beta8