|1.||Murakami, Akira: 15 articles (01/2015 - 05/2002)|
|2.||Abdul, Ahmad Bustamam: 10 articles (01/2015 - 08/2009)|
|3.||Ohigashi, Hajime: 8 articles (06/2011 - 05/2002)|
|4.||Aggarwal, Bharat B: 7 articles (01/2014 - 10/2005)|
|5.||Abdelwahab, Siddig Ibrahim: 6 articles (01/2015 - 08/2009)|
|6.||Rahman, Heshu Sulaiman: 5 articles (01/2015 - 01/2013)|
|7.||Sung, Bokyung: 5 articles (01/2014 - 10/2008)|
|8.||Mohan, Syam: 4 articles (01/2015 - 08/2010)|
|9.||Taha, Manal Mohamed Elhassan: 4 articles (01/2015 - 08/2009)|
|10.||Rasedee, Abdullah: 4 articles (01/2015 - 01/2013)|
|1.||Breast Neoplasms (Breast Cancer)
08/01/2014 - "Notch2 activation is protective against anticancer effects of zerumbone in human breast cancer cells."
11/01/2012 - "The present study was undertaken to determine the anticancer efficacy of zerumbone (ZER), a sesquiterpene from subtropical ginger, against human breast cancer cells in vitro and in vivo. "
12/01/2014 - "In the present study, we investigated the role of zerumbone (ZER) on regulatory mechanisms of CD44 expression in breast cancer cells. "
11/01/2014 - "Here, we investigated the effect of zerumbone (ZER) on IL-1β-induced cell migration and invasion in breast cancer cells. "
08/01/2014 - "We showed previously that zerumbone (ZER), a sesquiterpene isolated from subtropical ginger, inhibited in vitro (MCF-7 and MDA-MB-231cells) and in vivo (MDA-MB-231 cells) growth of human breast cancer cells in association with apoptosis induction. "
01/01/2013 - "Moreover, the histological evaluation of liver specimens demonstrated that the steatosis and inflammation in liver of zerumbone-treated groups were improved. "
01/01/2011 - "This study aims to determine the effect of zerumbone, a potent NF-κB inhibitor and inflammation modulators, on UVB-induced corneal damages in a mouse model. "
10/01/2010 - "Anti-inflammatory effect of zerumbone on acute and chronic inflammation models in mice."
02/01/2015 - "Zerumbone enhances the Th1 response and ameliorates ovalbumin-induced Th2 responses and airway inflammation in mice."
11/15/2015 - "The anti-proliferative activity of these compounds against the LU-1, Hep-G2, MCF-7 and SW480 human cancer cell lines were significantly improved compared to those of azazerumbone or zerumbone. "
11/15/2012 - "This review summarizes the data based on various in vitro and in vivo studies related to the effects of zerumbone on numerous pivotal molecular targets in cancer and its reported chemopreventive/therapeutic effects in different models of cancer."
07/01/2004 - "In our present study, the anti-tumor initiating and promoting activities of zerumbone in mouse skin were evaluated using a conventional 2-stage carcinogenesis model. "
11/01/2015 - "Zerumbone, a natural cyclic sesquiterpene, is known to exhibit selective toxicity toward various cancer cells. "
10/01/2015 - "Overall, our results suggest for the first time that zerumbone is a novel blocker of STAT3 signaling cascade and thus has an enormous potential for the treatment of RCC and other solid tumors."
|4.||Diabetic Nephropathies (Diabetic Nephropathy)
01/01/2013 - "The aim of the present study was to examine the effects of zerumbone in rats with streptozotocin-induced diabetic nephropathy (DN). "
01/01/2013 - "Zerumbone, a tropical ginger sesquiterpene, ameliorates streptozotocin-induced diabetic nephropathy in rats by reducing the hyperglycemia-induced inflammatory response."
|5.||Pancreatic Neoplasms (Pancreatic Cancer)
04/01/2014 - "Zerumbone inhibits angiogenesis by blocking NF-κB activity in pancreatic cancer."
11/01/2008 - "Suppression of CXCR4 expression by zerumbone correlated with the inhibition of CXCL12-induced invasion of both breast and pancreatic cancer cells. "
11/01/2008 - "The decrease in CXCR4 by zerumbone was found to be not cell type specific as its expression was abrogated in leukemic, skin, kidney, lung, and pancreatic cancer cell lines. "
01/01/2012 - "In summary, we found that zerumbone was able to induce apoptosis of pancreatic carcinoma cell lines, indicating to be a promising treatment for pancreatic cancer."
04/01/2014 - "Zerumbone, a component of subtropical ginger, has been shown to exhibit anticancer activities in various cancer cells; however, little is known about its biological mechanisms against angiogenesis in pancreatic cancer (PaCa). "
|6.||Interleukin-6 Receptors (Interleukin 6 Receptor)
|7.||Interleukin-6 (Interleukin 6)
|8.||Ethanol (Ethyl Alcohol)
|9.||ganoderic acid A
|2.||Heterologous Transplantation (Xenotransplantation)