HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

elarofiban

a GPIIb and GPIIIa receptor antagonist; structure in first source

Also Known As:

RWJ 53308; RWJ-53308; (S)-beta-((R)-1-(3-(4-Piperidyl)propionyl)nipecotamido)-3-pyridinepropionic acid, monohydrate

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - elarofiban: 2
  - Piperidines: 17
    - Nipecotic Acids
      - elarofiban: 2
- Heterocyclic Acids
  - Nipecotic Acids
    - elarofiban: 2

Experts

1.	Berndt, Mathias: 1 article (06/2018)
2.	Chae, Sun Young: 1 article (06/2018)
3.	Cho, Yong-Pil: 1 article (06/2018)
4.	Han, Youngjin: 1 article (06/2018)
5.	Jang, Seongsoo: 1 article (06/2018)
6.	Jin, Soyoung: 1 article (06/2018)
7.	Kim, Bohyun: 1 article (06/2018)
8.	Kim, Chanwoo: 1 article (06/2018)
9.	Koglin, Norman: 1 article (06/2018)
10.	Kwon, Tae-Won: 1 article (06/2018)

Related Diseases

1.

Thrombosis (Thrombus)

10/15/2001 - "RWJ-53308 reduces thrombus weight in a canine arteriovenous (AV) shunt model following intravenous (0.01-0.1 mg/kg) and oral (3 mg/kg) administration. "
06/29/2018 - "18F-GP1 is a derivative of elarofiban with a high affinity to activated platelet glycoprotein IIb/IIIa (GPIIb/IIIa) and favorable in vivo characteristics for thrombus imaging in preclinical models. "
10/15/2001 - "In a guinea pig carotid artery pinch-injury model, RWJ-53308 completely suppresses thrombus-induced cyclic flow reductions (CFR) at 0.7 mg/kg iv. RWJ-53308 also blocks thrombus formation in photoactivation- and ferric chloride-induced models of thrombosis in guinea pigs at 0.3 and 1 mg/kg iv, respectively. "

Related Drugs and Biologics

1.	Platelet Membrane Glycoproteins
2.	ferric chloride