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inositol heptakisphosphate

phosphate uptake stimulator; amino acid sequence in first source

Also Known As:

InsP7

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Alcohols: 595
  - Sugar Alcohols: 143
    - Inositol: 2982
      - Inositol Phosphates: 351
        inositol heptakisphosphate: 6
Carbohydrates: 22023
- Sugar Alcohols: 143
  - Inositol: 2982
    - Inositol Phosphates: 351
      - inositol heptakisphosphate: 6
- Sugar Phosphates: 20
  - Inositol Phosphates: 351
    - inositol heptakisphosphate: 6

Experts

1.	Jessen, Henning J: 2 articles (01/2017 - 02/2016)
2.	Brearley, Charles A: 1 article (05/2018)
3.	Chen, Kai-Yu: 1 article (05/2018)
4.	Chiou, Tzyy-Jen: 1 article (05/2018)
5.	Hsu, Yu-Ying: 1 article (05/2018)
6.	Kuo, Hui-Fen: 1 article (05/2018)
7.	Lin, Wei-Chi: 1 article (05/2018)
8.	Munnik, Teun: 1 article (05/2018)
9.	Elich, Mila: 1 article (01/2018)
10.	Sauer, Karsten: 1 article (01/2018)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2018 - "Recent studies have shown that beyond "canonical" turnover by the PIP3 phosphatases and tumor suppressors phosphatase and tensin homolog (PTEN) and SH2 domain-containing inositol-5-phosphatase-1 (SHIP-1/2), PIP3 function in hematopoietic cells can also be dampened through antagonism with the soluble PIP3 analogs inositol(1,3,4,5)tetrakisphosphate (IP4) and inositol-heptakisphosphate (IP7). "
2.	Starvation 05/19/2018 - "However, the level of d/l-Ins(3,4,5,6)P4 is not responsive to Pi starvation that instead manifests a shoot-specific increase in the InsP7 level. " 01/01/2017 - "Here, using a human intestinal epithelial cell line (HCT116), we show that levels of both 5-InsP7 and ATP decrease upon [Pi] starvation and subsequently recover during Pi replenishment. " 01/01/2023 - "That Arabidopsis ITPK4 has a KM for ATP in the tens of micromolar range, potentially explains how, despite the large-scale abolition of InsP6, InsP7 and InsP8 synthesis in Atitpk4 mutants, Atitpk4 lacks the phosphate starvation responses of Atitpk1 mutants. "
3.	Weight Gain 02/04/2016 - "Inositol pyrophosphates, such as diphospho-myo-inositol pentakisphosphates (InsP7), are an important family of signalling molecules, implicated in many cellular processes and therapeutic indications including insulin secretion, glucose homeostasis and weight gain. "
4.	Pathologic Processes 05/07/2013 - "However, the various physiological and pathological processes that involve InsP7 are not completely understood. "

Related Drugs and Biologics

1.	Inositol (Myoinositol)
2.	Phosphoric Monoester Hydrolases (Phosphatases)
3.	Tensins
4.	Adenosine Triphosphate (ATP)
5.	Diphosphates (Pyrophosphates)
6.	Phosphates (Orthophosphate)
7.	Glucose (Dextrose)

Related Therapies and Procedures

1.	Transcutaneous Electric Nerve Stimulation (TENS)