|1.||Hampe, Christiane S: 3 articles (01/2013 - 12/2005)|
|2.||Banga, J Paul: 2 articles (04/2008 - 12/2005)|
|3.||Hall, Tyler R: 2 articles (04/2008 - 12/2005)|
|4.||Widman, Guido: 1 article (01/2015)|
|5.||Witt, Juri-Alexander: 1 article (01/2015)|
|6.||Greschus, Susanne: 1 article (01/2015)|
|7.||Melzer, Nico: 1 article (01/2015)|
|8.||Golombeck, Kristin: 1 article (01/2015)|
|9.||Ermert, Johannes: 1 article (01/2015)|
|10.||Hautzel, Hubertus: 1 article (01/2015)|
05/01/2009 - "Association of the -243 A-->G polymorphism of the glutamate decarboxylase 2 gene with obesity in girls with premature pubarche."
04/01/2006 - "Lack of association of glutamate decarboxylase 2 gene polymorphisms with severe obesity in utah."
09/01/2005 - "Recently, three (-243 A>G, +61450 C>A, and +83897 T>A) single nucleotide polymorphisms (SNPs) within glutamate decarboxylase 2 (GAD2) were found to be associated with class III obesity (body mass index > 40 kg/m2). "
04/01/2005 - "Is glutamate decarboxylase 2 (GAD2) a genetic link between low birth weight and subsequent development of obesity in children?"
03/01/2012 - "Association of genetic polymorphisms of glutamate decarboxylase 2 and the dopamine D2 receptor with obesity in Taiwanese subjects."
09/30/1996 - "In localizing the two GABA-producing forms of glutamate decarboxylase (GAD65 and GAD67) in the normal hippocampus as a prelude to experimental epilepsy studies, we unexpectedly discovered that, in addition to its presence in hippocampal nonprincipal cells, GAD67-like immunoreactivity (LI) was present in the excitatory axons (the mossy fibers) of normal dentate granule cells of rats, mice, and the monkey Macaca nemestrina. "
|3.||Type 1 Diabetes Mellitus (Autoimmune Diabetes)
04/01/2008 - "Here we show that administration of a human monoclonal antibody (b96.11) specific to the 65-kDa isoform of glutamate decarboxylase (GAD65) to prediabetic non-obese diabetic (NOD) mice significantly delays the onset of autoimmune diabetes. "
04/01/2000 - "Newly diagnosed latent autoimmune diabetes in adults (LADA) is associated with low level glutamate decarboxylase (GAD65) and IA-2 autoantibodies. "
06/01/1997 - "Autoantibodies to the islet-cell 65-kDa variant of glutamate decarboxylase (GAD65) are found in most insulin-dependent diabetes mellitus (IDDM) patients many years before the appearance of clinical symptoms of the disease. "
01/01/1992 - "Years before IDDM symptoms appear, we can detect autoantibodies to one or both forms of glutamate decarboxylase (GAD65 and GAD67), synthesized from their respective cDNAs in a bacterial expression system. "
06/01/2000 - "Most insulin-dependent diabetes mellitus patients gen-erate conformational autoantibodies to the islet-cell 65-kDa variant of human glutamate decarboxylase (GAD65), and several immunochemical tests for the early detection of type-1 diabetes rely on GAD65 antibody (GADA) assessment using properly folded recombinant GAD65 as the antigen. "
|4.||Stiff-Person Syndrome (Stiff Man Syndrome)
12/01/2005 - "Autoantibodies to the 65-kDa isoform of glutamate decarboxylase GAD65 (GAD65Ab) are strong candidates for a pathological role in Stiff-Person syndrome (SPS). "
01/01/2013 - "Stiff Person Syndrome (SPS) is a rare autoimmune movement disorder characterized by the presence of autoantibodies specific to the smaller isoform of glutamate decarboxylase (GAD65). "
04/01/2005 - "The 65 kDa human isoform of glutamate decarboxylase, GAD65, plays a central role in neurotransmission in higher vertebrates and is a typical autoantigen in several human autoimmune diseases, such as insulin-dependent diabetes mellitus (IDDM), Stiff-man syndrome and autoimmune polyendocrine syndrome type I. In autoimmune diabetes, an attack of inflammatory cells to endocrine pancreatic beta-cells leads to their complete destruction, eventually resulting in the inability to produce sufficient insulin for the body's requirements. "
04/01/1996 - "Glutamate decarboxylase (GAD65) is a major autoantigen in insulin-dependent diabetes (IDDM) and the neurological disorder Stiff-Man-Syndrome (SMS). "
|5.||Limbic Encephalitis (Paraneoplastic Limbic Encephalitis)
|2.||gamma-Aminobutyric Acid (GABA)
|8.||Glutamate Decarboxylase (Decarboxylase, Glutamate)
|9.||Class 8 Receptor-Like Protein Tyrosine Phosphatases
|10.||Protein Isoforms (Isoforms)