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BnSO(2)-D-Arg-Gly-Arg-ketothiazole

structure in first source

Also Known As:

C 921-78; C921-78

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - BnSO(2)-D-Arg-Gly-Arg-ketothiazole: 2
Organic Chemicals: 133
- Sulfur Compounds: 278
  - Thiazoles: 392
    - BnSO(2)-D-Arg-Gly-Arg-ketothiazole: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Thiazoles: 392
      - BnSO(2)-D-Arg-Gly-Arg-ketothiazole: 2

Experts

1.	André, Patrick: 1 article (11/2003)
2.	Conley, Pamela B: 1 article (11/2003)
3.	Delaney, Suzanne M: 1 article (11/2003)
4.	LaRocca, Thomas: 1 article (11/2003)
5.	Lin, Pei Hua: 1 article (11/2003)
6.	Phillips, David R: 1 article (11/2003)
7.	Sinha, Uma: 1 article (11/2003)
8.	Vincent, Diana: 1 article (11/2003)
9.	Hollenbach, S J: 1 article (04/2000)
10.	Ku, P: 1 article (04/2000)

Related Diseases

1.	Venous Thrombosis (Deep-Vein Thrombosis) 04/21/2000 - "In the venous thrombosis model at the maximally effective dose, C921-78 had minimal extension of ex vivo clotting parameters, while enoxaparin and unfractionated heparin demonstrated a two to sevenfold increase in activated partial thromboplastin times, and PPACK had a threefold extension of thrombin clotting times. "
2.	Thrombosis (Thrombus) 11/25/2003 - "Thrombin and TXA2 also synergized with P2Y12 in the absence of anticoagulation, because combined treatment of aspirin or C921-78 (a factor Xa inhibitor) with CT50547 or 2-MeSAMP (a P2Y12 antagonist) inhibited the thrombotic process, whereas all treatments failed to inhibit thrombosis when used individually. "

Related Drugs and Biologics

1.	Thrombin
2.	Enoxaparin (Lovenox)
3.	Thromboplastin (Tissue Factor)
4.	Heparin (Liquaemin)
5.	Aspirin (Acetylsalicylic Acid)
6.	CT 50547
7.	phenylalanyl- prolyl- arginine- chloromethyl ketone (PPACK)
8.	A-factor (Streptomyces)