HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

OPC 28326

a hindlimb vasodilator; structure in first source

Also Known As:

4-(N-methyl-2-phenylethylamino)-1-(3,5-dimethyl-4-propionylaminobenzoyl)piperidine; OPC-28326

Networked: 4 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Aniline Compounds: 46
    - OPC 28326: 4
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperidines: 17
    - OPC 28326: 4

Experts

1.	Hashimoto, Ayako: 2 articles (07/2015 - 05/2007)
2.	Fujiwara, Hisayoshi: 1 article (07/2015)
3.	Fujiwara, Takako: 1 article (07/2015)
4.	Goto, Kazuko: 1 article (07/2015)
5.	Kanamori, Hiromitsu: 1 article (07/2015)
6.	Kawasaki, Masanori: 1 article (07/2015)
7.	Minatoguchi, Shinya: 1 article (07/2015)
8.	Miyakoda, Goro: 1 article (07/2015)
9.	Nagashima, Kenshi: 1 article (07/2015)
10.	Nakagawa, Munehiro: 1 article (07/2015)

Related Diseases

1.	Myocardial Infarction 07/01/2015 - "The purpose of this study was to examine the effect of OPC-28326 on the architectural dynamics and function of the infarcted left ventricle during the chronic stage of myocardial infarction. " 07/01/2015 - "Myocardial infarction was induced in male C3H/He mice, after which the mice were randomly assigned into two groups: a control group receiving a normal diet and an OPC group whose diet contained 0.05% OPC-28326. "
2.	Body Weight (Weight, Body) 11/01/2001 - "In the present study, we tested OPC-28326 in isoflurane anesthetized rats at a dose of 3 mg/kg of body weight, given intraduodenally. "
3.	Mydriasis 10/01/2001 - "Intravenous OPC-28326 had no effect on this action, even at a very high dose of 10 mg kg(-1) i.v., while yohimbine (0.1 - 0.3 mg kg(-1) i.v.) inhibited mydriasis in a dose-dependent manner, indicating that OPC-28326 was at least 100 times less potent than yohimbine in regard to the anti-mydriatic effect. "
4.	Vascular Diseases (Vascular Disease) 05/01/2007 - "OPC-28326 might be promising to treat patients with ischemic vascular diseases."
5.	Ischemia 05/01/2007 - "Next, the angiogenic effect of OPC-28326 was evaluated in a mouse hindlimb ischemia model. " 05/01/2007 - "Here, we investigated the effect of OPC-28326 on ischemia-induced angiogenesis. " 05/01/2007 - "OPC-28326, a selective femoral arterial vasodilator, augments ischemia induced angiogenesis."

Related Drugs and Biologics

1.	Isoflurane
2.	Yohimbine (Yocon)
3.	Vasodilator Agents (Vasodilators)
4.	Mydriatics (Cycloplegics)