|1.||Sawada, Norimasa: 13 articles (03/2015 - 12/2004)|
|2.||Kojima, Takashi: 10 articles (03/2015 - 12/2004)|
|3.||Morin, Patrice J: 8 articles (10/2009 - 07/2003)|
|4.||Santin, Alessandro D: 7 articles (04/2015 - 10/2004)|
|5.||Bellone, Stefania: 6 articles (12/2011 - 10/2004)|
|6.||Pecorelli, Sergio: 6 articles (12/2011 - 10/2004)|
|7.||Schaff, Zsuzsa: 6 articles (12/2011 - 03/2006)|
|8.||Murata, Masaki: 5 articles (03/2015 - 12/2004)|
|9.||Soini, Ylermi: 5 articles (06/2014 - 12/2004)|
|10.||Kulka, Janina: 5 articles (06/2013 - 03/2009)|
04/01/2014 - "All cases of mesothelioma were negative for claudin-4 (0 of 64). "
10/01/2013 - "All mesothelioma specimens were negative for claudin-4, but 3 of 18 specimens were focally positive for Ber-EP4. "
05/01/2013 - "Value of claudin-4 immunostaining in the diagnosis of mesothelioma."
08/01/2007 - "Claudin-4 in mesothelioma diagnosis."
04/01/2014 - "Claudin-4 immunohistochemistry is highly effective in distinguishing adenocarcinoma from malignant mesothelioma in effusion cytology."
12/01/2009 - "These results suggest that low claudin-4 expression in epitheliomas is a molecular characteristic indicative of increasing cellular disorientation, detachment motility and invasion by tumour cells, and claudin-4 seems to be helpful in distinguishing undifferentiated carcinomas from differentiated carcinomas and epitheliomas of the hepatoid gland. "
09/01/2015 - "This study aimed to investigate the expression of the intestinal claudin (claudin 4) in gastric carcinoma and to evaluate its relation to the different clinicopathologic prognostic parameters, especially lymphangiogenesis (production of new lymphatic vessels, measured by lymphovascular density (LVD)) and lymphovascular invasion (LVI). "
07/06/2012 - "In this study, we aimed to determine the role of Twist1 in the regulation of claudin-4 expression and investigate its specific mechanisms and clinical implications using human esophageal carcinoma cell lines and tissues. "
09/01/2015 - "So, claudin 4 may be used as one of the differentiating markers between the two major types of gastric carcinoma (intestinal vs. diffuse). "
09/01/2015 - "High expression of claudin 4 was associated with the more differentiated intestinal-type gastric carcinoma and lost in poorly differentiated diffuse type. "
09/01/2012 - "This review describes and discusses the studies targeting claudin-4 in normal human pancreatic duct epithelial (HPDE) cells and cancer cells. "
08/01/2015 - "Moreover, the size of tumor formation was reduced in nude mice transplanted with claudin-4 silenced MCF-7 cells. "
07/01/2015 - "Tumor cells were immunohistochemically positive for PAX8, claudin-4, and VE1, excluding the possibility of being of mesothelial origin. "
05/01/2015 - "Claudin-4 is overexpressed in several premalignant precursor lesions, including those of cancers of the breast, pancreas, and prostate, and is associated with poor survival. "
06/01/2014 - "However, there was a significant correlation between high expression of claudin 4 and cancer recurrence. "
|4.||Ovarian Neoplasms (Ovarian Cancer)
04/01/2011 - "Claudin-4 expression was significantly greater in ovarian cancer tissue from chemoresistant patients compared to chemosensitive patients. "
09/01/2009 - "Therapeutic antitumor efficacy of monoclonal antibody against Claudin-4 for pancreatic and ovarian cancers."
12/15/2011 - "CD44(+) ovarian cancer stem cells expressed claudin-4 gene at significantly higher levels than matched autologous CD44(-) ovarian cancer cells, and regardless of their higher resistance to chemotherapeutic agents died within 1 hour after exposure to 1.0 μg/mL of CPE in vitro. "
12/15/2011 - "During the characterization of CD44(+) ovarian cancer stem cells, we found a high expression of the genes encoding for claudin-4. "
04/01/2011 - "Claudin-4 expression in ovarian cancer tissue resected from the patients surgically was evaluated immunohistochemically. "
06/01/2014 - "Prognostic significance of claudin 4 in completely resected adenocarcinoma of the lung."
01/01/2014 - "Diagnostic value of claudin-4 marker in pleural and peritoneal effusion cytology: Does it differentiate between metastatic adenocarcinoma and reactive mesothelial cells?"
07/01/2012 - "Claudin-4 expression predicts survival in pancreatic ductal adenocarcinoma."
09/01/2008 - "Among them, most up-regulated genes, such as AQP3 and Claudin-4, were expressed in both adenocarcinoma cells and type II alveolar pneumocytes, corresponding to the histological similarity between these cell types. "
02/01/2006 - "In conclusion, claudin-4, MKK4, and stratifin immunolabeling detects precursor lesions of gastric adenocarcinoma that are otherwise clinically, radiographically, and endoscopically inapparent. "
|2.||claudin 1 (CLDN1)
|3.||Proteins (Proteins, Gene)
|10.||Galectin 3 (LGALS3)
|1.||Heterologous Transplantation (Xenotransplantation)
|2.||Drug Therapy (Chemotherapy)