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N,N-didesmethyltamoxifen

structure in first source

Also Known As:

N,N-DDT

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzylidene Compounds: 10
        Stilbenes: 657
        Tamoxifen: 14288
        N,N-didesmethyltamoxifen: 2

Experts

1.	Beland, Frederick A: 1 article (11/2007)
2.	Churchwell, Mona I: 1 article (11/2007)
3.	Doerge, Daniel R: 1 article (11/2007)
4.	Fu, Xin: 1 article (11/2007)
5.	Gamboa da Costa, Gonçalo: 1 article (11/2007)
6.	Marques, M Matilde: 1 article (11/2007)
7.	Wang, Yu-Ping: 1 article (11/2007)
8.	Beland, F A: 1 article (08/2001)
9.	Gamboa da Costa, G: 1 article (08/2001)
10.	Heflich, R H: 1 article (08/2001)

Related Diseases

1.	Neoplasms (Cancer) 08/01/2001 - "Since the contribution of these alpha-hydroxy metabolites of tamoxifen to the induction of endometrial tumors is presently unknown, we compared the extent of DNA adduct formation in liver and selected non-hepatic tissues of female Sprague-Dawley rats treated by gavage with tamoxifen, alpha-hydroxytamoxifen, N-desmethyltamoxifen, alpha-hydroxy-N-desmethyltamoxifen and N,N-didesmethyltamoxifen, or intraperitoneal injection with tamoxifen, alpha-hydroxytamoxifen, 3-hydroxytamoxifen and 4-hydroxytamoxifen. "
2.	Body Weight (Weight, Body) 11/18/2007 - "To test this hypothesis directly, we compared the extent of tamoxifen-DNA adduct formation in rats co-administered 27micromol N,N-didesmethyltamoxifen per kg body weight and either 27micromol tamoxifen per kg body weight or 27micromol alpha-hydroxytamoxifen per kg body weight daily for 7days. "

Related Drugs and Biologics

1.	DNA Adducts
2.	Tamoxifen
3.	alpha-hydroxytamoxifen
4.	droloxifene
5.	N-desmethyltamoxifen
6.	afimoxifene (hydroxytamoxifen)

Related Therapies and Procedures

1.	Intraperitoneal Injections