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MT 21

activates both caspase-3 and c-Jun-NH2-terminal kinase; induces apoptosis in leukemia HL-60 cells; structure in first source

Also Known As:

MT-21

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrroles: 369
      - MT 21: 4

Experts

1.	Bisceglia, Michele: 2 articles (11/2007 - 01/2005)
2.	Caletti, Giancarlo: 2 articles (11/2007 - 01/2005)
3.	Fusaroli, Pietro: 2 articles (11/2007 - 01/2005)
4.	Marchegiani, Attilio: 2 articles (11/2007 - 01/2005)
5.	Papadopoli, Giovanni: 2 articles (11/2007 - 01/2005)
6.	Spada, Alessia: 2 articles (11/2007 - 01/2005)
7.	Tucci, Antonio: 2 articles (11/2007 - 01/2005)
8.	Tucci, Primiano: 2 articles (11/2007 - 01/2005)
9.	Caravelli, Giancarlo: 1 article (11/2007)
10.	Catalano, Tiziana: 1 article (11/2007)

Related Diseases

1.	Infections 11/01/2007 - "By using a novel device, the Mt 21-42, we evaluated the potential of this important organic fluid in clinical practice, exploring its contribution to the diagnosis of Helicobacter pylori infection and atrophic gastritis of the oxyntic mucosa (AGOM). " 10/01/2005 - "We evaluated the reliability and clinical validity of data obtained using an innovative device (the "Mt 21-42") that analyzes gastric juice, thus allowing the identification of Helicobacter pylori infection and atrophic gastritis of the oxyntic mucosa during endoscopy. " 01/01/2005 - "Mt 21-42: development and validation of an automatic device proposed for the endoscopic diagnosis of Helicobacter pylori infection and atrophic gastritis."
2.	Atrophic Gastritis 11/01/2007 - "By using a novel device, the Mt 21-42, we evaluated the potential of this important organic fluid in clinical practice, exploring its contribution to the diagnosis of Helicobacter pylori infection and atrophic gastritis of the oxyntic mucosa (AGOM). " 10/01/2005 - "We evaluated the reliability and clinical validity of data obtained using an innovative device (the "Mt 21-42") that analyzes gastric juice, thus allowing the identification of Helicobacter pylori infection and atrophic gastritis of the oxyntic mucosa during endoscopy. " 01/01/2005 - "Mt 21-42: development and validation of an automatic device proposed for the endoscopic diagnosis of Helicobacter pylori infection and atrophic gastritis."
3.	Leukemia 09/16/1999 - "One of our synthetic compounds, MT-21, induced apoptosis in human leukemia HL-60 cells similar to Fas. "
4.	Atrophy 10/01/2005 - "When compared with the currently available standard methods, use of the Mt 21-42 was found to be the most sensitive technique for the detection of atrophy (94.7 % vs. 5.3 % - 47.4 %; P < 0.001); the device failed to detect the disease in only one case (5 %), whereas failure rates of 53 % - 95 % were reported with the conventional methods. "