|1.||Lee, Tat Leang: 2 articles (01/2012 - 01/2006)|
|2.||Tachibana, Shinro: 2 articles (01/2012 - 01/2006)|
|3.||Vieira da Costa-Ribeiro, Magda Clara: 1 article (03/2015)|
|4.||Baura, Walter: 1 article (03/2015)|
|5.||de Castro, Edilene Alcântara: 1 article (03/2015)|
|6.||Pinto, Mara Cristina: 1 article (03/2015)|
|7.||Goulart, Thais Marchi: 1 article (03/2015)|
|8.||Baum, Maurício: 1 article (03/2015)|
|9.||Klisiowicz, Débora do Rocio: 1 article (03/2015)|
|10.||Kleinschmidt-Demasters, B K: 1 article (12/2012)|
|1.||Schizophrenia (Dementia Praecox)
01/01/2001 - "The human prepronociceptin (ppNoc) gene is located on chromosome 8p21, and several linkage studies have suggested that the susceptibility locus for schizophrenia is present in this chromosomal region. "
01/01/2001 - "Association analysis of polymorphisms in the prepronociceptin gene and schizophrenia."
06/01/2001 - "Genetic association studies of schizophrenia using the 8p21-22 genes: prepronociceptin (PNOC), neuronal nicotinic cholinergic receptor alpha polypeptide 2 (CHRNA2) and arylamine N-acetyltransferase 1 (NAT1)."
|2.||Neuralgia (Stump Neuralgia)
01/06/2012 - "We found that N/OFQ and prepronociceptin concentrations were significantly raised in both rat neuropathic pain models. "
01/06/2012 - "In this study, we investigated whether the prepronociceptin, N/OFQ and nocistatin concentrations in the brain and spinal cord would be altered in chronic constriction injury and diabetic rat neuropathic pain models. "
01/06/2012 - "Elevated prepronociceptin, nociceptin/orphanin FQ and nocistatin concentrations in rat chronic constriction nerve injury and diabetic neuropathic pain models."
01/06/2012 - "Overall, our data have demonstrated for the first time that prepronociceptin, N/OFQ and nocistatin concentrations are significantly altered at different tissues of two rat neuropathy pain models."
01/01/2006 - "Nocistatin (NST) and nociceptin/orphanin FQ (NCP) are two important bio-peptides derived from the precursor protein prepronociceptin (ppNCP), involved in several central nervous system (CNS) functions including pain transmission. "
07/01/1998 - "b-nocistatin is a heptadecapeptide produced from bovine prepronociceptin and blocks the induction of hyperalgesia and touch-evoked pain (allodynia) by intrathecal administration of nociceptin or prostaglandin E2 (PGE2). "
07/01/2001 - "We have shown, using reverse transcription-polymerase chain reaction (RT-PCR), that carrageenan-produced peripheral inflammation induces the expression of prepronociceptin (PPN) mRNA in the dorsal root ganglia (DRG). "
07/01/2001 - "Induction by carrageenan inflammation of prepronociceptin mRNA in VR1-immunoreactive neurons in rat dorsal root ganglia."
08/18/1997 - "Although little or no expression of prepronociceptin mRNA was observed in the dorsal root ganglia of naive animals, carrageenan-elicited inflammation markedly induced its expression, peaking within 30 min, a time when nociceptive hypersensitivity was not yet apparent. "
08/18/1997 - "To investigate whether the biosynthesis of nociceptin is altered in animals with nociceptive hypersensitivity, we examined effects of peripheral inflammation on the expression of prepronociceptin mRNA, especially in the dorsal root ganglion of the rat. "
|2.||DNA (Deoxyribonucleic Acid)
|5.||Messenger RNA (mRNA)