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ADM 10

structure in first source

Also Known As:

2-(3-dimethylaminopropyl)tricyclo(3.3.1.1(3,7))decan-2-ol bromide salt; ADM-10

Networked: 8 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Anniko, Matti: 1 article (11/2010)
2.	Cheng, Jun-Ping: 1 article (11/2010)
3.	Li, Wei: 1 article (11/2010)
4.	Zhang, Lun: 1 article (11/2010)
5.	Zhang, Wen-Chao: 1 article (11/2010)
6.	Cao, J: 1 article (04/2000)
7.	Wang, X: 1 article (04/2000)
8.	Zhang, J: 1 article (04/2000)

Related Diseases

1.	Neoplasms (Cancer) 09/01/1986 - "He was treated with 600 mg of UFT orally every day and ADM (10 mg, iv, on days 1-4, repeated every 14 days), resulting in marked regression (PR, partial response) of both the primary tumor and liver metastasis on the 33 rd day after the start of treatment, with decreasing of serum levels of AFP and CEA. " 03/01/1990 - "His serum AFP level had markedly increased to 115 X 10(4) ng/ml. His AFP level also elevated and multiple lung metastatic tumors appeared after the second TAE therapy of 30 mg ADM, 10 mg MMC. "
2.	Neoplasm Metastasis (Metastasis) 09/01/1986 - "He was treated with 600 mg of UFT orally every day and ADM (10 mg, iv, on days 1-4, repeated every 14 days), resulting in marked regression (PR, partial response) of both the primary tumor and liver metastasis on the 33 rd day after the start of treatment, with decreasing of serum levels of AFP and CEA. " 11/01/1989 - "However, after hepatic arterial infusion of ADM (10 mg/body) suspended in a lipiodol (3 ml/body) and CDDP (100 mg/body) was performed, liver metastases were remarkably regressive by abdominal CT. "
3.	Wounds and Injuries (Trauma) 11/01/2010 - "Satisfactory healing was observed between the wound margin and ADM 10 days after operation. "
4.	Ischemia 04/01/2000 - "In isolated perfused rat heart models, when Adm (10(-7) mol/L) was added in perfusion fluid for 15 minutes reperfusion after 45 minutes ischemic period, +/-LVdp/dt max of the heart increased 76.9% and 67.9%, and the average volume of coronary efflux increased 48.8%, respectively, compared with that of control group of ischemia-reperfusion. "
5.	Inflammation (Inflammations) 02/15/2023 - "In vitro experiments, ADM (10 nM) in A7r5 cells (rat thoracic aorta smooth muscle cells) attenuated palmitic acid (PA, 200 μM) or angiotensin II (Ang II, 10 nM) alone or their combination treatment-induced inflammation, oxidative stress and calcification, which were effectively inhibited by the ADM receptor antagonist ADM22-52 and AMP-activated protein kinase (AMPK) inhibitor Compound C, respectively. "

Related Drugs and Biologics

1.	AMP-Activated Protein Kinases
2.	Palmitic Acid (Hexadecanoic Acid)
3.	Ethiodized Oil (Ethiodol)
4.	Angiotensin II
5.	dorsomorphin
6.	4- chloro- 3',6'- dimethyl- 2,2'- iminodibenzoate (TO 115)

Related Therapies and Procedures

1.	Therapeutics