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1-(3-fluoropropyl)-2-nitroimidazole

lipophilic compound used for imaging hypoxia

Also Known As:

FPN, imidazole

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - 1-(3-fluoropropyl)-2-nitroimidazole: 2
Organic Chemicals: 133
- Nitro Compounds: 66
  - 1-(3-fluoropropyl)-2-nitroimidazole: 2

Experts

1.	Ando, Koichi: 1 article (05/2002)
2.	Aoki, Mizuho: 1 article (05/2002)
3.	Furusawa, Yoshiya: 1 article (05/2002)
4.	Kuwabara, Yasuo: 1 article (05/2002)
5.	Maeda, Minoru: 1 article (05/2002)
6.	Masuda, Kouji: 1 article (05/2002)
7.	Sasaki, Shigeki: 1 article (05/2002)
8.	Yamamoto, Fumihiko: 1 article (05/2002)

Related Diseases

1.

Brain Hypoxia (Cerebral Hypoxia)

06/01/1999 - "In order to develop new imaging markers for brain hypoxia, two lipophilic nitroimidazoles, 1-(3-fluoropropyl)-2-nitroimidazole (FPN) and 1-(8-fluorooctyl)-2-nitroimidazole (FON) were synthesized and labeled with fluorine-18. "
05/01/2002 - "In order to develop new imaging markers for brain hypoxia, 4-bromo-1-(3-fluoropropyl)-2-nitroimidazole (4-BrFPN) was designed based on molecular orbital calculations, synthesized and labeled with fluorine-18 as a lipophilic nitroimidazole analog with a lower energy LUMO orbital than those for fluoromisonidazole (FMISO) and 1-(3-fluoropropyl)-2-nitroimidazole (FPN). "

Related Drugs and Biologics

1.	Nitroimidazoles
2.	Fluorine-18
3.	4- bromo- 1- (3- fluoropropyl)- 2- nitroimidazole
4.	1-(8-fluorooctyl)-2-nitroimidazole
5.	fluoromisonidazole