|1.||Yokoyama, Osamu: 5 articles (05/2015 - 06/2011)|
|2.||Homma, Yukio: 5 articles (04/2015 - 09/2008)|
|3.||Akino, Hironobu: 4 articles (05/2015 - 06/2011)|
|4.||Yamaguchi, Osamu: 4 articles (09/2013 - 09/2008)|
|5.||Kitagawa, Yasuhide: 3 articles (05/2015 - 01/2011)|
|6.||Namiki, Mikio: 3 articles (05/2015 - 01/2011)|
|7.||Yamada, Shizuo: 3 articles (01/2014 - 02/2011)|
|8.||Ito, Yoshihiko: 3 articles (01/2014 - 02/2011)|
|9.||Masumori, Naoya: 3 articles (10/2013 - 01/2011)|
|10.||Kobayashi, Fumiyoshi: 3 articles (05/2008 - 01/2007)|
|1.||Overactive Urinary Bladder (Overactive Bladder)
10/01/2008 - "To evaluate the long-term safety, tolerability, and efficacy of imidafenacin, a novel anti-muscarinic agent, in Japanese patients with overactive bladder. "
10/01/2008 - "Long-term safety, tolerability, and efficacy of the novel anti-muscarinic agent imidafenacin in Japanese patients with overactive bladder."
10/01/2008 - "Men and women who had overactive bladder symptoms were enrolled for open-label treatment with 0.1 mg of imidafenacin twice daily for 52 weeks; the safety and efficacy of the treatment regimen were assessed. "
10/01/2013 - "Clinical efficacy and safety of imidafenacin as add-on treatment for persistent overactive bladder symptoms despite α-blocker treatment in patients with BPH: the ADDITION study."
09/01/2008 - "A randomized, double-blind, placebo-controlled phase II dose-finding study of the novel anti-muscarinic agent imidafenacin in Japanese patients with overactive bladder."
06/01/2013 - "Imidafenacin was effective in OAB patients with urgency and nocturia. "
09/01/2012 - "Administration of imidafenacin at 0.1-0.2 mg once daily before sleeping was safe and effective for the treatment of OAB with the main symptom of nocturia."
01/01/2012 - "We conclude that imidafenacin is an effective and safe drug for nocturia in patients with OAB."
01/01/2012 - "The efficacy of imidafenacin on nocturia is attributable to an increase in bladder capacity and a decrease in nocturnal urine volume. "
09/01/2013 - "Imidafenacin, an antimuscarinic agent, improves nocturia and reduces nocturnal urine volume."
01/01/2012 - "Treatment with imidafenacin significantly reduced the nocturnal polyuria index only in patients aged 75 years or over. "
07/01/2013 - "By subgroup analysis of the data set from a phase III clinical trial of antimuscarinic agent for OAB patients in Japan, imidafenacin was found to improve nocturia with a reduction in nocturnal polyuria. "
05/01/2015 - "To evaluate the efficacy and safety of imidafenacin (IM), a novel short half-life anticholinergic, as add-on therapy for male LUTS with nocturia and nocturnal polyuria. "
09/01/2013 - "The novel antimuscarinic agent, imidafenacin, decreases the number of urinations and reduces nocturnal urine production, thereby improving both nocturia and nocturnal polyuria."
09/01/2013 - "To evaluate the efficacy of imidafenacin for nocturia and nocturnal polyuria in patients with overactive bladder. "
06/01/2013 - "In addition, imidafenacin secondarily mitigated sleep disorders significantly. "
06/01/2013 - "[The efficacy of imidafenacin in patients with over active bladder, nocturia, or sleep disorders (Sayama-Iruma-Hannou study)]."
06/01/2013 - "The effect of imidafenacin for the treatment of over active bladder (OAB), in 100 patients with urgency, nocturia or sleep disorders was examined by an open-labeled, non-randomized,non-controlled study. "
01/01/2013 - "Several short-term clinical studies have demonstrated that imidafenacin also improves sleep disorders, nocturia, and nocturia-related quality of life. "
01/01/2011 - "Imidafenacin was effective in female patients with urge and mixed urinary incontinence. "
01/01/2011 - "[Efficacy and safety of imidafenacin in female patients with urge and mixed urinary incontinence]."
07/01/2007 - "We synthesized the six presumed metabolites (2--7) of 4-(2-methyl-1H-imidazol-1-yl)-2,2-diphenylbutanamide [KRP-197/ONO-8025, 1], a urinary incontinence therapeutic agent, in order to confirm the structures of the metabolites. "
01/01/2011 - "The effect of imidafenacin for the treatment of overactive bladder (OAB), in female patients with urge and mixed urinary incontinence was examined. "
|1.||quinuclidin- 3'- yl- 1- phenyl- 1,2,3,4- tetrahydroisoquinoline- 2- carboxylate monosuccinate (solifenacin)
|5.||Muscarinic Receptors (Muscarinic Acetylcholine Receptor)
|9.||Acetylcholine (Acetylcholine Chloride)