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1- (2- (9- octadecenoyloxy)ethyl)- 2- (8- heptadecenyl)- 3- (hydroxyethyl)imidazolinium

cationic lipid used to complex with DNA as an expression vector for delivering genes in vivo

Also Known As:

DOTIM; DOTIM chloride

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - 1-(2-(9-octadecenoyloxy)ethyl)-2-(8-heptadecenyl)-3-(hydroxyethyl)imidazolinium: 1
Lipids: 114793
- 1-(2-(9-octadecenoyloxy)ethyl)-2-(8-heptadecenyl)-3-(hydroxyethyl)imidazolinium: 1

Experts

1.	Dickinson, Peter J: 1 article (04/2004)
2.	Dow, Steven W: 1 article (04/2004)
3.	Higgins, Robert J: 1 article (04/2004)
4.	Jimenez, Daniel F: 1 article (04/2004)
5.	LeCouteur, Richard A: 1 article (04/2004)
6.	McKisic, Maureen: 1 article (04/2004)
7.	Tripp, Linda D: 1 article (04/2004)

Related Diseases

1.	Glioblastoma (Glioblastoma Multiforme) 04/01/2004 - "A DOTIM-cholesterol cationic liposome complexed to non-coding plasmid DNA (EV-CLDC) was administered intravenously (i.v.) at weekly intervals to 6-week-old male mice of the B6D2F1 strain at either 3, 10 or 17 days post-inoculation (DPI) of 4C8 glioblastoma cells. "

Related Drugs and Biologics

1.	Liposomes (Liposome)
2.	DNA (Deoxyribonucleic Acid)
3.	Cholesterol