Ro 70-0004

an alpha(1A)-adrenoceptor antagonist; structure in first source

Also Known As:

3-(3-(4-(fluoro-2-(2,2,2-trifluoroethoxy)phenyl)piperazin-1-yl)propyl)-5-methyl-1H-pyrimidine-2,4-dione monohydrochloride monohydrate; RS 100975; RS-100975; Ro-70-0004

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Pyrimidinones: 71
      - Uracil: 1493
        Thymine: 735
        Ro 70-0004: 1
  - Piperazines: 26
    - Ro 70-0004: 1

Related Diseases

1.	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 05/01/1999 - "The alpha1A-AR subtype selectivity of Ro 70-0004 and RS-100329, demonstrated in both cloned and native systems, should allow for an evaluation of the clinical utility of a 'uroselective' agent for the treatment of symptoms associated with benign prostatic hyperplasia."

Related Drugs and Biologics

1.	RS 100329