sophoricoside

05/22/2013 - "Collectively, the findings of this study provide us with novel insights into the pharmacological actions of sophoricoside as a potential molecule for use in the treatment of allergic inflammation diseases."
05/22/2013 - "The aim of the present study was to elucidate whether and how sophoricoside modulates the mast cell-mediated allergic inflammation in vitro and in vivo. "
02/01/2021 - "The effects of sophoricoside were determined in vivo by OVA- and TNCB-induced AD-like allergic skin inflammation in mice. "
05/22/2013 - "The ameliorative effect of sophoricoside on mast cell-mediated allergic inflammation in vivo and in vitro."
02/01/2021 - "To investigate the role of sophoricoside on AD-like allergic skin inflammation induced by ovalbumin (OVA) or 2,4,6-trinitrochlorobenzene (TNCB) in mouse models. "

11/27/2020 - "The study aims to evaluate protective effects of sophoricoside (Sop) on cardiac hypertrophy. "
11/27/2020 - "Sophoricoside ameliorates cardiac hypertrophy by activating AMPK/mTORC1-mediated autophagy."

01/01/2021 - "Overall, we demonstrated that sophoricoside improved allergic asthma by suppressing mast cell activation and CD4+ T cell differentiation."
01/01/2021 - "The aim of this study was to investigate the effects of sophoricoside from Sophora japonica on allergic asthma. "
01/01/2021 - "Sophoricoside from Sophora japonica ameliorates allergic asthma by preventing mast cell activation and CD4+ T cell differentiation in ovalbumin-induced mice."

02/01/2021 - "Topical application of sophoricoside decreased the symptoms of AD-like allergic skin inflammation, including elevated hypertrophic scars with spongiotic epidermis, epidermal hyperplasia, hyperkeratosis, infiltration of immune, and mast cells, dermal thickness, amounts of immunoglobulins, and pro-inflammatory cytokines, and the mast cell population in the skin. "

02/01/2021 - "Topical application of sophoricoside decreased the symptoms of AD-like allergic skin inflammation, including elevated hypertrophic scars with spongiotic epidermis, epidermal hyperplasia, hyperkeratosis, infiltration of immune, and mast cells, dermal thickness, amounts of immunoglobulins, and pro-inflammatory cytokines, and the mast cell population in the skin. "