|1.||Zheng, Yingru: 3 articles (10/2012 - 10/2011)|
|2.||Zhang, Li: 3 articles (10/2012 - 10/2011)|
|3.||Liu, Dongbo: 3 articles (10/2012 - 10/2011)|
|4.||Zhou, Peng: 3 articles (10/2012 - 10/2011)|
|5.||He, Fengtian: 3 articles (10/2012 - 10/2011)|
|6.||Jagodziński, Paweł P: 2 articles (01/2015 - 01/2013)|
|7.||Chen, Zhu: 2 articles (02/2014 - 01/2013)|
|8.||Xu, Jie: 2 articles (02/2014 - 01/2013)|
|9.||Chen, Sai-Juan: 2 articles (02/2014 - 01/2013)|
|10.||Qi, Weidong: 1 article (12/2015)|
|1.||Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
07/20/2011 - "To study the incidence and prognostic impact of mutations in DNA methyltransferase 3A (DNMT3A) in patients with acute myeloid leukemia. "
04/01/2011 - "New studies reveal that 20% of individuals with acute myeloid leukemia harbor somatic mutations in DNMT3A (encoding DNA methyltransferase 3A). "
04/01/2015 - "DNA methyltransferase 3A (DNMT3A) is one of the commonly mutated genes in acute myelogenous leukemia (AML). "
01/01/2015 - "We demonstrate that aberrant hypermethylation within the gene DNA methyltransferase 3A (DNMT3A) - which may contribute to initiation of acute myeloid leukemia (AML) - is particularly observed in AML samples that reveal significantly more age-associated DNAm changes. "
02/18/2014 - "The gene encoding DNA methyltransferase 3A (DNMT3A) is mutated in ∼20% of acute myeloid leukemia cases, with Arg882 (R882) as the hotspot. "
12/01/2015 - "Genetic Polymorphism of DNA Methyltransferase 3A rs1550117 A>G and Risk of Cancer: A Meta-analysis."
04/02/2015 - "Inhibition of intestinal tumor formation by deletion of the DNA methyltransferase 3a."
10/01/2011 - "Differential expression of Oct4 in HPV-positive and HPV-negative cervical cancer cells is not regulated by DNA methyltransferase 3A."
08/01/2012 - "In this study, we found that the level of Oct4 in human papillomavirus 16 (HPV16)- positive cervical cancer cells (CaSki cells) was higher than that in HPV-negative cervical cancer cells (C-33A cells), whereas both the level of histone deacetylase 1 (HDAC1) and DNA methyltransferase 3A (DNMT3A) were lower in CaSki cells than those in C-33A cells. "
10/01/2012 - "Both the levels of histone deacetylase 1 (HDAC1) and DNA methyltransferase 3A (DNMT3A) were negatively correlated with the level of Oct4 in cervical cancer cells. "
|3.||Breast Neoplasms (Breast Cancer)
10/01/2015 - "In this study we utilized a programmable DNA-binding methyltransferase to induce targeted incorporation of DNA methylation (DNAme) in the SOX2 oncogene in breast cancer through a six zinc finger (ZF) protein linked to DNA methyltransferase 3A (ZF-DNMT3A). "
10/01/2012 - "However, DNA methyltransferase 3a overexpression was found less frequently in the luminal A intrinsic breast cancer subtype (9.7%) than in luminal B (53%), HER2 (41%), and triple-negative (50%) subtypes (P = .001). "
01/01/2013 - "Therefore, we investigated whether miRNA-29b, due to its complimentarity to the 3'- untranslated region of DNA methyltransferase 3A (DNMT3A) and DNMT3B, could restore normal DNA methylation patterns in human breast cancers and breast cancer cell lines. "
04/01/2012 - "We show that site-specific DNA methylation and long-term stable repression of the tumor suppressor Maspin and the oncogene SOX2 can be achieved in breast cancer cells via zinc-finger ATFs targeting DNA methyltransferase 3a (DNMT3a) to the promoters of these genes. "
03/01/2014 - "Ectopic expression of miR-143 inhibited proliferation and soft agar colony formation of breast cancer cells and also downregulated DNA methyltransferase 3A (DNMT3A) expression on both mRNA and protein levels. "
03/01/2013 - "Other mutations in the JAK-STAT signalling cascade are reviewed, including JAK2 exon 12, myeloproliferative leukemia virus oncogene, LNK (also known as SH2B3) mutations, and epigenetic changes in ten-eleven-translocation-2 (TET2), additional sex combs like 1 (ASXL1), PcG enhancer of zeste homolog 2 (EZH2) and DNA methyltransferase 3A (DNMT3A). "
06/01/2012 - "Prognostic significance of DNA methyltransferase 3A mutations in cytogenetically normal acute myeloid leukemia: a study by the Acute Leukemia French Association."
01/01/2013 - "Mouse models with conditional knockout of the DNA methyltransferase 1 (DNMT1) and DNA methyltransferase 3A (DNMT3A) genes have revealed a role of DNA methylation in mediating the self-renewal and differentiation of normal hematopoietic stem cells (HSCs) and the leukemia stem cells (LSCs). "
|5.||Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
|1.||DNA (Deoxyribonucleic Acid)
|2.||Histone Deacetylase 1
|3.||Messenger RNA (mRNA)
|7.||Caspase 3 (Caspase-3)
|8.||5-Methylcytosine (5 Methylcytosine)
|9.||Cannabinoid Receptors (Cannabinoid Receptor)
|10.||Ephrin-A1 (Ephrin A1)