McrBC endonuclease

recognizes and cleaves methylated DNA in reaction dependent on GTP hydrolysis; requires at least 2 recognition sites separated by 40-80 bp, may be as far as 3 kb apart; see also records for components endodeoxyribonuclease McrB and mcrC protein

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Esterases: 1574
      - Deoxyribonucleases: 1259
        Endodeoxyribonucleases
        DNA Restriction Enzymes: 848
        McrBC endonuclease: 1
      - Endonucleases: 1227
        Endodeoxyribonucleases
        DNA Restriction Enzymes: 848
        McrBC endonuclease: 1
  - DNA Restriction-Modification Enzymes: 41
    - DNA Restriction Enzymes: 848
      - McrBC endonuclease: 1

Experts

1.	Brøndsted, Lone: 1 article (01/2021)
2.	Chichkova, Mariana A T: 1 article (01/2021)
3.	Fanger, Florian: 1 article (01/2021)
4.	Gencay, Yilmaz Emre: 1 article (01/2021)
5.	Klumpp, Jochen: 1 article (01/2021)
6.	Mazúrová, Mária: 1 article (01/2021)
7.	Nielsen, Eva M: 1 article (01/2021)
8.	Sørensen, Martine C H: 1 article (01/2021)

Related Diseases

1.	Subacute Sclerosing Panencephalitis (SSPE) 01/01/2021 - "Sequence divergence was also observed in a predicted SspE homolog and putative restriction modification systems including a methyl-specific McrBC endonuclease. "

Related Drugs and Biologics

1.	DNA Restriction-Modification Enzymes (Restriction Modification Systems)