|1.||Park, Kwang-Kyun: 5 articles (04/2013 - 05/2004)|
|2.||Hwang, Jae Kwan: 5 articles (04/2013 - 05/2004)|
|3.||Chung, Won-Yoon: 4 articles (04/2013 - 05/2004)|
|4.||Hwang, Jae-Kwan: 4 articles (05/2011 - 01/2005)|
|5.||Abdullah, Noor Rain: 3 articles (01/2009 - 11/2006)|
|6.||Cheah, Yew Hoong: 3 articles (01/2009 - 11/2006)|
|7.||Azimahtol, Hawariah Lope Pihie: 3 articles (01/2009 - 11/2006)|
|8.||Kim, Seong Hwan: 3 articles (01/2005 - 05/2004)|
|9.||Lee, Sang Kook: 2 articles (11/2009 - 06/2007)|
|10.||Nordin, Fariza Juliana: 2 articles (01/2009 - 11/2008)|
01/01/2014 - "This study also identified 2 putative components, xanthorrhizol and marmelosin, which could be imparting the immunoprophylactic and antitumor effects in transplantable tumor models. "
11/01/2009 - "In the present study, we investigated the growth inhibitory effect of xanthorrhizol on cancer cells. "
04/01/2013 - "Xanthorrhizol, a natural sesquiterpenoid compound isolated from Curcuma xanthorrhiza Roxb, has been known to inhibit the growth of human colon, breast, liver and cervical cancer cells. "
11/01/2009 - "These findings provide one plausible mechanism for the growth inhibitory activity of xanthorrhizol against cancer cells."
03/01/2007 - "The apoptosis mediated by xanthorrhizol in the HepG2 cells was associated with the activation of tumor suppressor p53 and down-regulation of antiapoptotic Bcl-2 protein expression, but not Bax. "
|2.||Breast Neoplasms (Breast Cancer)
11/01/2008 - "In our study, we tested the antiproliferative effect of xanthorrhizol using different breast cancer cell lines. "
11/01/2008 - "Antiproliferative property and apoptotic effect of xanthorrhizol on MDA-MB-231 breast cancer cells."
11/01/2006 - "Xanthorrhizol exhibits antiproliferative activity on MCF-7 breast cancer cells via apoptosis induction."
01/01/2014 - "This study investigated the herb-drug interaction of xanthorrhizol and tamoxifen in human breast cancer cells. "
01/01/2009 - "The present study was undertaken to evaluate the possibility that the combination of xanthorrhizol and curcumin might show synergistic growth inhibitory effect towards MDA-MB-231 human breast cancer cells via apoptosis induction. "
|3.||Hepatocellular Carcinoma (Hepatoma)
03/01/2007 - "This study investigated the antiproliferative effect and the mechanism of action of xanthorrhizol on human hepatoma cells, HepG2, and the mode of cell death. "
04/20/2012 - "Previously, we have reported that xanthorrhizol inhibited the proliferation of HepG2 human hepatoma cells by inducing apoptotic cell death via caspase activation. "
03/01/2007 - "Regulation of p53-, Bcl-2- and caspase-dependent signaling pathway in xanthorrhizol-induced apoptosis of HepG2 hepatoma cells."
|4.||Neoplasm Metastasis (Metastasis)
01/07/2005 - "In conclusion, xanthorrhizol exerts anti-metastatic activity in vivo and this effect could be highly linked to the metastasis-related multiplex signal pathway including ERK, COX-2, and MMP-9."
01/07/2005 - "Xanthorrhizol, a natural sesquiterpenoid from Curcuma xanthorrhiza, has an anti-metastatic potential in experimental mouse lung metastasis model."
01/07/2005 - "In this study, the anti-metastatic activity of xanthorrhizol was evaluated by using an in vivo mouse lung metastasis model and a tumor mass formation assay. "
01/07/2005 - "Next, to examine the mechanism of the anti-metastatic action of xanthorrhizol in the mouse lung metastasis, expression patterns of the several intracellular signaling molecules were evaluated using the lung tissues with tumor nodules. "
|5.||Liver Neoplasms (Liver Cancer)
|1.||Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)
|2.||Cyclooxygenase 2 (Cyclooxygenase-2)
|5.||Mitogen-Activated Protein Kinases
|6.||NF-kappa B (NF-kB)
|10.||Methylene Blue (Methylthioninium Chloride)