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separase

caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase; RefSeq NM_012291 (human); GenBank L07289 (S. cerevisiae)
Also Known As:
ESP1 protein, S cerevisiae; ESPL1 protein, human; Separase, Drosophila; Sse protein, Drosophila; YGR098C protein, S cerevisiae; extra spindle poles like 1 (S. cerevisiae) protein, human; separin
Networked: 28 relevant articles (0 outcomes, 4 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Pati, Debananda: 5 articles (08/2014 - 09/2008)
2. Zhang, Nenggang: 5 articles (08/2014 - 09/2008)
3. Hofmann, Wolf-Karsten: 3 articles (01/2015 - 01/2012)
4. Seifarth, Wolfgang: 3 articles (01/2015 - 01/2012)
5. Fabarius, Alice: 3 articles (01/2015 - 01/2012)
6. Haaß, Wiltrud: 3 articles (01/2015 - 01/2012)
7. Zhang, Pumin: 3 articles (01/2014 - 01/2008)
8. Huang, Xingxu: 3 articles (01/2011 - 01/2008)
9. Müller, Martin C: 2 articles (01/2015 - 01/2015)
10. Kleiner, Helga: 2 articles (01/2015 - 01/2015)

Related Diseases

1. Neoplasms (Cancer)
2. Genomic Instability
3. Aneuploidy (Aneuploid)
4. Polyploidy
5. Neoplasm Metastasis (Metastasis)

Related Drugs and Biologics

1. cohesins (cohesin)
2. Cysteine Proteases (Cysteine Protease)
3. Cyclin B2
4. Cyclin B1
5. Small Interfering RNA (siRNA)
6. Ubiquitin
7. Paclitaxel (Taxol)
8. Cyclins
9. Tetracycline (Achromycin)
10. Phosphotransferases (Kinase)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Transplants (Transplant)
3. Hepatectomy