|1.||Lee, Wei Ling: 1 article (12/2007)|
|2.||Chen, Peng Min: 1 article (12/2007)|
|3.||Tang, Yong Cheng: 1 article (12/2007)|
|4.||Tsai, Mui Chiung: 1 article (12/2007)|
|5.||Tang, Feng Ru: 1 article (12/2007)|
|6.||Porreca, F: 1 article (10/2000)|
|7.||Dogrul, A: 1 article (10/2000)|
|8.||Malan, T P: 1 article (10/2000)|
|9.||Lai, J: 1 article (10/2000)|
|10.||Ossipov, M H: 1 article (10/2000)|
|1.||Status Epilepticus (Complex Partial Status Epilepticus)
12/01/2007 - "By intravenous administration of group I metabotropic glutamate receptor antagonists at 1 or 2h during pilocarpine induced status epilepticus (PISE), we showed that mGluR1 antagonists AIDA or LY367385 (at dosages ranging from 25 to 200mg/kg), mGluR5 antagonists SIB1757 (at dosages ranging from 25 to 200mg/kg), SIB1893 (from 25 to 100mg/kg), MPEP (from 25 to 100mg/kg) injected at 1 or 2h during PISE were ineffective in controlling status epilepticus (SE). "
|2.||Neuralgia (Stump Neuralgia)
10/06/2000 - "Here, the possible role of mGluR(5) receptors in experimental neuropathic pain elicited by ligation of spinal nerves (L(5)/L(6) spinal nerve ligation, SNL) was explored with SIB-1757, a selective mGluR(5) antagonist. "
10/06/2000 - "Peripheral and spinal antihyperalgesic activity of SIB-1757, a metabotropic glutamate receptor (mGLUR(5)) antagonist, in experimental neuropathic pain in rats."
10/06/2000 - "SIB-1757 produced full reversal of thermal hyperalgesia in SNL rats following administration either spinally or locally to the injured paw; administration to the contralateral paw had no effect. "
10/06/2000 - "SIB-1757 produced a partial reversal of tactile allodynia with a shallow dose-response curve ranging over three-orders of magnitude; SIB-1757 was inactive against allodynia when given systemically. "
|1.||Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)
|4.||metabotropic glutamate receptor type 1
|5.||metabotropic glutamate receptor 5