HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

HYB 165

a DNA/RNA hybrid, RIalpha mixed-backbone oligonucleotide containing 2'-O-methylribonucleotides; currently undergoing Phase I clinical trials

Also Known As:

HYB-165

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleotides: 15763
  - Polynucleotides: 218
    - Oligonucleotides: 5145
      - HYB 165: 1

Related Diseases

1.

Breast Neoplasms (Breast Cancer)

04/01/1999 - "These findings provide the basis for a novel strategy of treatment of breast cancer patients because both HYB 165 and MAb C225 are presently under clinical evaluation."
04/01/1999 - "We have shown that HYB 165 exhibits a dose-dependent inhibitory effect on ZR-75-1 cells and a cooperative activity with docetaxel, a cytotoxic drug active in breast cancer. "

Related Drugs and Biologics

1.	Docetaxel (Taxotere)
2.	Cetuximab (Erbitux)