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Phlogenzym

consists of bromelain, trypsin and the anti-oxidant rutosid; used to treat immune-mediated inflammatory conditions

Networked: 15 relevant articles (3 outcomes, 6 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Daftary, G V: 2 articles (04/2002 - 06/2001)
2.	Schiess, W: 2 articles (04/2002 - 06/2001)
3.	Turakhia, N H: 2 articles (04/2002 - 06/2001)
4.	Buchbinder, Rachelle: 1 article (06/2016)
5.	Deitch, Jessica: 1 article (06/2016)
6.	Green, Sally: 1 article (06/2016)
7.	Lyttle, Nicolette: 1 article (06/2016)
8.	McBain, Brodwen: 1 article (06/2016)
9.	Mrocki, Marshall A: 1 article (06/2016)
10.	Page, Matthew J: 1 article (06/2016)

Related Diseases

1.	Multiple Sclerosis 04/01/2003 - "An assessment was carried out of clinical effectiveness of the drug phlogenzym in 74 patients with remitting, remitting-progressive, and secondary progressive course of multiple sclerosis. " 04/01/2003 - "[Effect of phlogenzym in long-term treatment of patients with multiple sclerosis]." 05/01/1999 - "Clinical trials that test the efficacy of Phlogenzym (consisting of the hydrolytic enzymes bromelain and trypsin and the anti-oxidant rutosid) as a treatment for T cell-mediated autoimmune diseases including multiple sclerosis (MS), type 1 diabetes and rheumatoid arthritis are presently ongoing. "
2.	Hepatitis C 06/01/2005 - "Data from a randomized trial in hepatitis C infected Egyptian patients suggest that the oral intake of the enzyme preparation Phlogenzym results in a significant reduction of aminotransferase levels and is equally effective to the therapy with interferon alpha. "
3.	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 05/01/1999 - "Clinical trials that test the efficacy of Phlogenzym (consisting of the hydrolytic enzymes bromelain and trypsin and the anti-oxidant rutosid) as a treatment for T cell-mediated autoimmune diseases including multiple sclerosis (MS), type 1 diabetes and rheumatoid arthritis are presently ongoing. "
4.	Autoimmune Diseases (Autoimmune Disease) 05/01/1999 - "These data show the efficacy of oral Phlogenzym treatment in an animal model of T cell-mediated autoimmune disease and suggest that the protective effect might be the result of an increase in the activation threshold of the autoreactive T lymphocytes brought about by the cleavage of accessory molecules involved in the interaction of T cells and antigen presenting cells." 05/01/1999 - "Clinical trials that test the efficacy of Phlogenzym (consisting of the hydrolytic enzymes bromelain and trypsin and the anti-oxidant rutosid) as a treatment for T cell-mediated autoimmune diseases including multiple sclerosis (MS), type 1 diabetes and rheumatoid arthritis are presently ongoing. "
5.	Rheumatoid Arthritis 05/01/1999 - "Clinical trials that test the efficacy of Phlogenzym (consisting of the hydrolytic enzymes bromelain and trypsin and the anti-oxidant rutosid) as a treatment for T cell-mediated autoimmune diseases including multiple sclerosis (MS), type 1 diabetes and rheumatoid arthritis are presently ongoing. "

Related Drugs and Biologics

1.	Enzymes
2.	Trypsin
3.	Bromelains (Bromelain)
4.	Antioxidants
5.	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)
6.	Interferon-alpha (Interferon Alfa)
7.	Transaminases (Aminotransferases)
8.	Rutin (Rutoside)
9.	Tablets
10.	Diclofenac (SR 38)

Related Therapies and Procedures

1.	Therapeutics
2.	Enzyme Therapy
3.	Musculoskeletal Manipulations (Manipulative Therapy)
4.	Nephrectomy