|1.||Coyle, Joseph T: 3 articles (01/2015 - 01/2010)|
|2.||Hashimoto, Kenji: 3 articles (01/2013 - 06/2005)|
|3.||Labrie, Viviane: 3 articles (03/2012 - 09/2009)|
|4.||Roder, John C: 3 articles (03/2012 - 09/2009)|
|5.||Barger, Steven W: 3 articles (02/2012 - 09/2009)|
|6.||Wu, Shengzhou: 2 articles (01/2016 - 01/2011)|
|7.||Jiang, Haiyan: 2 articles (01/2016 - 01/2011)|
|8.||Puhl, Matthew D: 2 articles (01/2015 - 06/2013)|
|9.||Sasabe, Jumpei: 2 articles (12/2014 - 09/2007)|
|10.||Konno, Ryuichi: 2 articles (12/2014 - 06/2012)|
|1.||Schizophrenia (Dementia Praecox)
01/01/2015 - "In vivo magnetic resonance studies reveal neuroanatomical and neurochemical abnormalities in the serine racemase knockout mouse model of schizophrenia."
09/01/2009 - "Serine racemase is associated with schizophrenia susceptibility in humans and in a mouse model."
05/15/2007 - "A genetic variant of the serine racemase gene is associated with schizophrenia."
04/01/2007 - "No association between the serine racemase gene (SRR) and schizophrenia in a German case-control sample."
07/31/2006 - "Serine racemase protein expression in cortex and hippocampus in schizophrenia."
|2.||Type 2 Diabetes Mellitus (MODY)
12/01/2011 - "1. The aim of this study was to investigate the association of the serine racemase (SRR) rs391300 G/A polymorphism with the risk of diabetes mellitus type 2 (T2DM) and to assess the impacts of the polymorphism on the therapeutic efficacy of metformin in Chinese patients. "
12/01/2011 - "Serine racemase rs391300 G/A polymorphism influences the therapeutic efficacy of metformin in Chinese patients with diabetes mellitus type 2."
01/01/2013 - "Cellular concentrations of D-serine are regulated by synthesis due to the enzyme serine racemase (isomerization reaction) and by degradation due to the same enzyme(elimination reaction) as well as by the FAD-containing flavoenzyme D-amino acid oxidase (DAAO, oxidative deamination reaction).Several findings have linked low levels of D-serine to schizophrenia: D-serine concentrations in serum and cerebrospinal fluid have been reported to be decreased in schizophrenia patients while human DAAO activity and expression are increased; oral administration of D-serine improved positive, negative, and cognitive symptoms of schizophrenia as add-on therapy to typical and atypical antipsychotics.This"
|4.||Brain Ischemia (Cerebral Ischemia)
04/01/2004 - "To study the alterations of the expressions of serine racemase in C57BL/6 mouse brain after permanent focal cerebral ischemia. "
01/27/2010 - "Serine racemase deletion protects against cerebral ischemia and excitotoxicity."
04/01/2004 - "Serine racemase expression in mouse cerebral cortex after permanent focal cerebral ischemia."
04/01/2004 - "Delayed decreases in serine racemase expression and D-serine level occurred in the temporoparietal cortex at the late stage after focal cerebral ischemia."
01/01/2014 - "Increased sensitivity to inflammatory pain induced by subcutaneous formalin injection in serine racemase knock-out mice."
06/27/2012 - "To clarify the functional roles of endogenous d-serine in chronic pain-induced plasticity of NMDAR mediated synaptic transmission, we investigated the NMDAR-mediated excitatory synaptic current (EPSC) of neurons in the latero-capsular division of the central amygdala (CeLC) using brain slices from serine racemase knockout (SR-KO) mice with chronic pain induced by monoarthritis. "
01/01/2012 - "Antinociceptive effect of rat D-serine racemase inhibitors, L-serine-O-sulfate, and L-erythro-3-hydroxyaspartate in an arthritic pain model."
09/01/2013 - "Furthermore, the administration of D-amino-acid oxidase (DAAO), a D-serine-degrading enzyme, or that of L-serine O-sulfate (LSOS), a serine racemase inhibitor, significantly decreased pain behavior in allodynic rats. "
|2.||D-Amino-Acid Oxidase (D-Amino Acid Dehydrogenase)
|4.||Antipsychotic Agents (Antipsychotics)
|5.||Flavin-Adenine Dinucleotide (FAD)
|6.||N-Methyl-D-Aspartate Receptors (NMDA Receptors)
|7.||Messenger RNA (mRNA)
|9.||Nitric Oxide (Nitrogen Monoxide)