poncirin

02/15/2022 - "Poncirin ameliorates cardiac ischemia-reperfusion injury by activating PI3K/AKT/PGC-1α signaling."
02/15/2022 - "In conclusion, both in vitro and in vivo studies suggested that poncirin alleviates cardiac ischemia-reperfusion injury by mitigating oxidative stress, which is dependent on activation of the PI3K/AKT/PGC-1α signaling pathway."
01/01/2022 - "Poncirin ameliorates oxygen glucose deprivation/reperfusion injury in cortical neurons via inhibiting NOX4-mediated NLRP3 inflammasome activation."

04/24/2013 - "Thus, poncirin from Ougan fruit, may be beneficial for gastric cancer prevention. "
09/18/2015 - "This result suggests that the mitochondrial-mediated pathway is not involved in Poncirin-induced cell death in gastric cancer. "
04/24/2013 - "The chemical structure of the purified poncirin was identified by both HPLC-PDA and LC-MS. Poncirin showed a significant in vitro inhibitory effect on the growth of the human gastric cancer cells, SGC-7901, in a dose-dependent manner. "
09/18/2015 - "These findings suggest that Poncirin has a potential anti-cancer effect via extrinsic pathway-mediated apoptosis, possibly making it a strong therapeutic agent for human gastric cancer. "
09/18/2015 - "Poncirin Induces Apoptosis in AGS Human Gastric Cancer Cells through Extrinsic Apoptotic Pathway by up-Regulation of Fas Ligand."

11/01/2020 - "Poncirin suppresses lipopolysaccharide (LPS)-induced microglial inflammation and ameliorates brain ischemic injury in experimental stroke in mice."
08/02/2016 - "The fruit of Poncirus trifoliate, which contains poncirin as a main constituent, is frequently used in the traditional Chinese medicine for inflammation, asthma, and infection diseases. "
01/01/2021 - "Pharmacological data analysis revealed the biological application of poncirin against bone loss, inflammation, colitis, human gastric cancer, gastritis, liver injury and Alzheimer's disease. "

12/01/2009 - "Protective effects of neohesperidin and poncirin isolated from the fruits of Poncirus trifoliata on potential gastric disease."
01/01/2021 - "The biological importance of poncirin against bacterial, viral infections, gastric disease and human gastric cancer has been investigated in medicine. "

11/01/2020 - "Poncirin suppresses lipopolysaccharide (LPS)-induced microglial inflammation and ameliorates brain ischemic injury in experimental stroke in mice."