RS 14203

a type IV cyclic nucleotide phosphodiesterase inhibitor; structure in first source

Also Known As:

RS-14203; RS14203

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

1.	Vomiting 02/01/1999 - "The incidence of emesis was positively influenced by the dose of PDE IV inhibitors administered, allowing a rank order of potency: RS14203 > R-rolipram > S-rolipram > CT-2450 > CT-3405. " 02/01/1999 - "Emesis induced by RS14203 exhibited a dose-response relationship but no such relationship was seen for R-rolipram or CT-2450. "
2.	Bradycardia 09/01/2000 - "RS14203, (R)-rolipram, or CT-2450 (1-100 microg/kg iv) did not affect the bradycardia induced by vagal electrical stimulation. "