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4-phosphonophenylglycine

structure in first source

Also Known As:

(R,S)-4-phosphonophenylglycine; 4-PPG cpd

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Glycine: 5151
    - 4-phosphonophenylglycine: 4

Experts

1.	Folbergrová, Jaroslava: 1 article (03/2003)
2.	Haugvicová, Renata: 1 article (03/2003)
3.	Mares, Pavel: 1 article (03/2003)
4.	Burnashev, N: 1 article (11/2001)
5.	Bushell, T J: 1 article (11/2001)
6.	Clarke, V R: 1 article (11/2001)
7.	Collett, V J: 1 article (11/2001)
8.	Collingridge, G L: 1 article (11/2001)
9.	Duvoisin, R M: 1 article (11/2001)
10.	Flor, P J: 1 article (11/2001)

Related Diseases

1.	Seizures (Absence Seizure) 10/21/1999 - "We have used intracerebroventricular administration to test a novel group III agonist, (R,S)-4-phosphonophenylglycine (PPG), that is preferential for mglu(8), against sound-induced seizures in DBA/2 mice. " 11/15/2001 - "PTZ-induced seizures were inhibited by three standard anticonvulsant drugs, but not by the group III selective mGluR agonist (R,S)-4-phosphonophenylglycine (PPG). " 03/01/2003 - "Seizures induced by homocysteic acid in immature rats are prevented by group III metabotropic glutamate receptoragonist (R,S)-4-phosphonophenylglycine." 03/01/2003 - "The potential anticonvulsant effect of group III metabotropic glutamate receptor (mGluR) agonist (R,S)-4-phosphonophenylglycine ((R,S)-PPG) against seizures induced in immature 12-day-old rats by bilateral intracerebroventricular (icv) infusion of DL-homocysteic acid (DL-HCA, 600 nmol/side) was examined in the present study. "
2.	Brain Injuries (Brain Injury) 05/01/2001 - "Fifty male Sprague-Dawley rats were subjected to lateral fluid percussion brain injury immediately followed by an intracranial injection of 2-(2',3')-dicarboxycyclopropylglycine (DCG-IV) (Group II) or (R,S)-4-phosphonophenylglycine (Group III) in the CA2 and CA3 areas of the hippocampus. "

Related Drugs and Biologics

1.	Anticonvulsants (Antiepileptic Drugs)
2.	Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)
3.	homocysteic acid
4.	Glutamic Acid (Glutamate)
5.	2-(2,3-dicarboxycyclopropyl)glycine