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Ts-gamma neurotoxin

isolated from Tityus serrulatus

Also Known As:

TiTX gamma; Tityus toxin gamma; neurotoxin Ts-gamma; toxin Ts-gamma

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Complex Mixtures: 1906
- Venoms: 4328
  - Arthropod Venoms: 770
    - Scorpion Venoms: 373
      - Ts-gamma neurotoxin: 2
Biological Factors: 2472
- Biological Toxins: 20
  - Venoms: 4328
    - Arthropod Venoms: 770
      - Scorpion Venoms: 373
        Ts-gamma neurotoxin: 2

Related Diseases

1.

07/01/1984 - "The binding of radiolabelled TiTx gamma to the Na channels in the neuroblastoma cell membrane is prevented by native TiTx gamma with a K0.5 = 0.75 nM. Both activation and inactivation of the TiTx gamma-induced Na current are shifted 30-40 mV towards more negative potential values as compared to normally voltage-dependent Na current. "
01/01/1984 - "The neurotoxic action of toxin gamma from the venom of the Brazilian scorpion Tityus serrulatus (TiTx gamma) has been investigated in cultured mouse neuroblastoma cells (N1E115) using the suction pipette technique. "
07/01/1984 - "The effects of highly purified toxin gamma from the venom of the scorpion Tityus serrulatus (TiTx gamma) on nerve membrane ionic channels have been investigated using the suction electrodes voltage clamp technique on neuroblastoma cells. "

Related Drugs and Biologics

1.	Venoms
2.	Ion Channels (Ion Channel)

Related Therapies and Procedures

1.	Electrodes (Electrode)