T 3811ME

structure in first source

Also Known As:

1-cyclopropyl-8-(difluoromethoxy)-7-(1-methyl-2,3-dihydro-1H-5-isoindolyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid methanesulfonate monohydrate; T-3811ME

Networked: 3 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinolines: 146
      - Quinolones: 2938
        T 3811ME: 3
    - Isoindoles: 18
      - T 3811ME: 3

Experts

1.	Furubou, Shinichi: 1 article (06/2002)
2.	Minami, Shinzaburo: 1 article (06/2002)
3.	Morita, Teiichi: 1 article (06/2002)
4.	Narita, Hirokazu: 1 article (06/2002)
5.	Takahata, Masahiro: 1 article (06/2002)
6.	Todo, Yozo: 1 article (06/2002)
7.	Watanabe, Yasuo: 1 article (06/2002)
8.	Yamada, Hiroshi: 1 article (06/2002)
9.	Hori, R: 1 article (01/2001)
10.	Kizawa, K: 1 article (01/2001)

Related Diseases

1.	Pneumonia (Pneumonitis) 05/01/1999 - "aureus and experimental pneumonia with PRSP in mice, T-3811ME showed excellent therapeutic efficacy in oral and subcutaneous administrations." 01/01/2001 - "pneumoniae pneumonia model in hamsters, after the administration of T-3811ME (20 mg/kg of body weight as T-3811, once daily, orally) for 5 days, the reduction of viable cells of M. "
2.	Body Weight (Weight, Body) 06/01/2002 - "After the intravenous dosing of T-3811ME (20 mg/kg of body weight as T-3811) in rabbits with meningitis caused by PRSP, the area under the concentration-time curve (AUC) of T-3811 in cerebrospinal fluid (CSF) was 5.79 microg. " 01/01/2001 - "pneumoniae pneumonia model in hamsters, after the administration of T-3811ME (20 mg/kg of body weight as T-3811, once daily, orally) for 5 days, the reduction of viable cells of M. "
3.	Meningitis 06/01/2002 - "After the intravenous dosing of T-3811ME (20 mg/kg of body weight as T-3811) in rabbits with meningitis caused by PRSP, the area under the concentration-time curve (AUC) of T-3811 in cerebrospinal fluid (CSF) was 5.79 microg. " 06/01/2002 - "T-3811ME (BMS-284756) may be expected to be evaluated for the management of meningitis caused by highly penicillin-resistant pneumococci." 06/01/2002 - "Evaluation of T-3811ME (BMS-284756), a new des-F(6)-quinolone, for treatment of meningitis caused by penicillin-resistant Streptococcus pneumoniae in rabbits."

Related Drugs and Biologics

1.	Penicillins (Penicillin)